In this guide, we provide an overview of the DDR and innate immune pathway and describe Transcreener Assays and Assay Systems for key targets.
There is extensive crosstalk between the DNA damage response (DDR) and innate immune pathways. Both are a focus for exciting new small-molecule drug therapeutics that target cancers and autoimmune disorders. The Transcreener HTS Assay platform accelerates these efforts by providing robust and easy-to-use biochemical assays for key enzymes in the pathways. In this guide, we provide an overview of the DDR and innate immune pathways and describe assay systems for key therapeutic targets.
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Using biochemical assays to study the DDR and innate immunity
Nucleotidyltransferases
Nucleotidases and Glycohydrolases
Helicases and exonucleases
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