Application note: Effect of perfluorinated alcohols in impurity analysis for synthetic oligonucleotides
Posted: 7 August 2020 | Phenomenex | No comments yet
Therapeutic oligonucleotides represent a recent breakthrough in the pharmaceutical industry.
Improved reliability to synthetic routes coupled with new drug delivery technologies has given a heightened level of interest in these clinically interesting targets. However, characterisation of oligos, specifically by ion-pair reversed phase liquid chromatography (IP-RPLC), can be quite challenging.
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Analysis, Analytical Techniques, Biopharmaceuticals, Disease Research, Gene Testing, Genetic Analysis, Genome Editing, Genomics, Mass Spectrometry, Personalised Medicine
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