Drug Target Review Screening ebook

Professor Ventsislav Valev from the University of Bath and Nicholas Kotov from University of Michigan write about their discovery of a new non-linear chiroptical effect based on non-linear scattering processes in semiconductor nanohelices, enabling chiroptical characterisation of nanohelices in volumes as minuscule as 1µL, which is suitable for the creation of large libraries of bioactive nanostructures.

To overcome some obstacles to greater throughput for drug testing using cell-based models, Dr Tijmen Booij and Dr Christian Stirnimann from ETH Zurich, Switzerland have developed an organoid drug-screening platform with numerous benefits including being animal-free, cheap to run and pipette-tip free, reducing plastic waste in screening assays.

In this ebook:

• Chiral nanostructures could help accelerate drug discovery
  Professor Nicholas Kotov, Irving Langmuir Distinguished University Professor at the University of Michigan and Professor Ventsislav Valev, Professor of Physics and Research Fellow of the Royal Society, University of Bath
• Miniaturising organoid drug screens using nanofibrillar cellulose hydrogels
  Dr Tijmen Booij and Dr Christian Stirnimann from ETH Zurich, Switzerland