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Naegleria fowleri infections are rare but almost invariably fatal, with pathologic sequelae spawning its common label as ‘the brain-eating amoeba’. Researchers identified two unique proteins within N. fowleri – self-activating guanine nucleotide-hydrolysing proteins (G proteins) – that present novel targets for drug discovery. This article summarises their work to date,…
In this interview we discuss with Alder Therapeutics regenerative cell therapy development through a proactive strategy, addressing manufacturing challenges early and ensuring a streamlined process. We explore an approach in pluripotent stem cell therapy development which eliminates complexities, minimises costs and expedites the delivery of transformative therapies.
A new discovery about the dynamic structure of norovirus particles has implications for vaccine development.
Researchers developed a personalised stem cell therapy using a data-driven, single-cell technique based on swift subcellular proteomic imaging.
Biomarkers found through urinary and exosome proteome profiling have potential for diagnosis and disease monitoring.
Founder and CSO of Achilles Therapeutics Dr Sergio Quezada reveals how the landmark TRACERx study has gleaned key insights that could make the difference between success and failure in immunotherapy treatment.
Cofounder & Chief Scientific Officer of Pheast Therapeutics, Dr Roy Maute, reveals his company’s promising drug candidate and explains why they have focused on their chosen target.
22 December 2023 | By
Download now! Drug Target Review breaks down the potential of stem cells for personalised regenerative medicine, offering practical insights into their role in healthcare.
In this special December edition of Women in STEM, we are privileged to feature Dr Catherine Sheehan, a distinguished figure whose journey in the field of STEM has been marked by passion, resilience, and impactful contributions. We explore her experiences, challenges faced, and the transformative impact of her work in…
22 December 2023 | By
Download this eBook for FREE. Explore cutting-edge immuno-oncology insights through exclusive interviews and studies by leading experts in the field.
From a database of more than 200,000 high-resolution, three-dimensional images of human induced pluripotent stem cells, researchers have devised a model to quantify cell shape and internal organisation. Susanne Rafelski, Deputy Director of the Allen Institute for Cell Science, revealed details of their study to Drug Target Review.
21 December 2023 | By
A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.
In the rapidly evolving landscape of mRNA biology and artificial intelligence (AI), Anima Biotech stands at the forefront, a unique approach that reshapes our understanding of diseases and transforms the drug discovery process. mRNA biology holds immense potential with RNAi drugs in the market and mRNA vaccines showing promise, particularly…
The first multi-chamber cardioids derived from hiPSCs have enabled scientists to investigate heart development and defects.
In a world grappling with the growing spectre of eco-anxiety and the pressing challenges posed by climate change, Dr Judy Illes, a distinguished figure in the field of neuroscience, sheds light on the role neuroscientists play in contributing to the discourse on environmental issues and their profound impact on individual…
