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KCNB1 may be a root cause of Alzheimer’s disease
Researchers have identified that levels of the protein KCNB1 are increased in Alzheimer's brains, which may cause the increase of amyloid-beta plaques...
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Alzheimer’s disease
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Amyloid beta – a good therapeutic target?
Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...
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Tau protein disrupts molecular transport in neurons in Alzheimer’s
Researchers have discovered how the tau protein associated with Alzheimer's affects molecular transport and a nucleporin called Nup98...
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Making an early link between cognitive impairment and Alzheimer’s
Researchers in the U.S. have devised a novel strategy to effectively identify those individuals with mild cognitive impairment that will most likely go on to develop Alzheimer's disease.
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New lead for Alzheimer’s research proposed
Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...
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Potential indicator for the early detection of dementias
A team of neuropathologists worked together to show that the impairments affecting mitochondria also affect neighbouring organelles...
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pH imbalance in astrocytes may lead to Alzheimer’s disease
The researchers found that 10 of the 100 most frequently down-regulated genes were connected with proton flow in the cell...
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miR-132 offers hope for novel Alzheimer’s treatments
The study of neuroprotective microRNAs like miR-132 may lead to new avenues for treating Alzheimer's disease and other tau pathologies...
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CMPK2 inhibitor could lesson symptoms of common illnesses
CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
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Curcumin eye drops may treat glaucoma
A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma...
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New 3D ‘nanoscope’ facilitates improved brain imaging for Alzheimer’s research
Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.
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Study pinpoints the ‘Big Bang’ of tau-induced Alzheimer’s neurodegeneration
Scientists in the U.S. have identified what they believe to be the genesis of Alzheimer's disease – the precise point at which a healthy tau protein becomes toxic but has not yet formed deadly tangles in the brain. The finding opens up numerous avenues for treatment research.
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Nuclear medicine technique to gauge impact of gene therapy
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively address brain conditions such as Parkinson's disease, Alzheimer's disease and multiple sclerosis.
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NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
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Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.