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APOE4 gene variant linked to Alzheimer’s
A study reveals why people with the APOE4 gene have a higher risk of the disease...
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Alzheimer’s disease
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Scientists reveal model that estimates lifetime risk of developing Alzheimer’s dementia
The Alzheimer’s Association have published a study wherein a model estimates the lifetime risk of an individual developing Alzheimer’s disease dementia. The risk varies with such factors as age and gender, and crucially takes account of preclinical biological changes.
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Lab-on-a-chip device mimics eye damage due to intense light
Researchers create eye neuron network model to study retinal diseases, possible treatment options...
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Cambinol halts spread of toxic protein associated with Alzheimer’s progression
Research could help lead to the design of drugs that slow neurodegeneration...
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CRISPR used to edit DNA outside of the cell
Scientists have developed a breakthrough CRISPR gene-editing tool, that could allow researchers to quickly and precisely engineer multiple changes to the genetic code...
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New method allows scientists to watch brain cells interacting in real time
Findings could deepen understanding of neurological disorders...
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Detecting diminished dopamine cells could reveal early signs of Alzheimer’s
A new link between diminished input from dopamine-firing cells could be crucial in detecting the earliest signs of Alzheimer's disease...
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Ultrathin endoscope captures neurons firing deep in the brain
A new fibre-based endoscope, tested in mice, poised to bring new insights into brain function...
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Nicotinic receptor research paves way for targeted dementia therapy
A new study which identifies how acetylcholine impacts learning and memory by acting at different receptors could prove significant in the drive to develop more targeted and effective therapies for dementia...
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Alzheimer’s patients exhibit changes in certain blood lipids typical of premature ageing
Research at MedUni Vienna’s Centre for Brain Research has investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer’s disease.
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Change in neuron size could shed light on new treatments for ALS
Understanding how motor nerve cells respond to motor neurone disease could help researchers identify new treatment options...
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Researchers evaluate tau phosphorylation related targets for Alzheimer’s research
Scientists in Moscow have extended the reach of QSP modelling by applying it to tau phosphorylation to better understand Alzheimer’s disease (AD) progression.
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GAPSA reveals new HIV targets
Researchers have developed the first-ever high-throughput, genome-scale imaging-based approach to investigate protein stability...
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Single-cell RNA sequencing provides molecular atlas to study brain diseases
Researchers have detailed a molecular atlas of the cells that form the brain's blood vessels and the life-essential blood-brain barrier providing clues to which cell types are involved in different diseases...
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Depleting BACE1 reverse the formation of amyloid plaques in Alzheimer’s disease
A team of researchers from the have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's disease...