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Anxiety

news

XCL1 could mitigate psychiatric condition risk in offspring

29 April 2024 | By Drug Target Review

Adult anxious behaviour in offspring may be related to the early life proinflammatory state caused by the absence of elevated XCL1.

news

DOP-targeted therapies could exert significant anxiolytic effects

23 February 2024 | By Drug Target Review

Researchers have uncovered the role of the PL-BLA neuronal axis and its potential function in DOP-mediated anxiolytic effects.

article

Growth hormone’s influence on neuropsychiatric disorders

10 January 2024 | By Ellen Capon (Drug Target Review)

The discovery of a mechanism involving anxiolytic effects of GH may lead to the development of new classes of anxiolytic drugs.

3d illustration. Model of serotonin molecule

news

Scientists discover multiple pathways of the 5HT2a receptor activated by psychedelics

4 October 2022 | By Ria Kakkad (Drug Target Review)

The new LSD-like compounds activated the 5HT2a receptor, a receptor stimulated by serotonin, without causing hallucinations.

news

CRISPR-dCas9 gene editing reverses brain genetic reprogramming caused by adolescent binge drinking

11 May 2022 | By Ria Kakkad (Drug Target Review)

A new study in animals has shown that gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence.

article

Innovative treatments: the new frontier for mental health

10 March 2022 | By Adrien Châtillon (Actipulse Neuroscience)

In this exclusive piece, Adrien Châtillon, Co-Founder and CEO of Actipulse Neuroscience, explores the future of treatment for diseases that impact mental health.

cartoon of the cross-section of a purple ion channel in a blue lipid bylayer (plasma mebrane)

news

New insight to guide discovery of drugs targeting ion channels

24 November 2020 | By Hannah Balfour (Drug Target Review)

The study shows how drug-like small molecules inhibit the activity of Transient Receptor Potential Canonical 1/4/5 (TRPC1/4/5) channels and could transform the development of future therapies.

news

Novel antibody treatment for OCD demonstrates efficacy in mice

22 April 2020 | By Victoria Rees (Drug Target Review)

Researchers who administered an antibody to neutralise an OCD-associated protein in mice found it reduced their anxious behaviours.

news

Researchers identify potential drug target for depression in primates

15 August 2019 | By Nic Losardo (Drug Target Review)

A study has discovered a molecule key in neuronal growth that could be used as a drug target to treat anxiety-related diseases.

news

Marijuana component may help treat anxiety and substance abuse disorders

9 March 2017 | By British Journal of Pharmacology

Cannabidiol shown to affect emotion and emotional memory

news

New avenue for anti-depressant therapy discovered

20 January 2017 | By Niamh Marriott (Drug Target Review)

Researchers have made a ground-breaking discovery revealing new molecular information on how the brain regulates depression and anxiety.

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Anxiety