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Larval protein could suppress inflammatory reactions, say researchers
A study has revealed that a protein of roundworm larvae which needs to invade the intestines of rodents to survive could be used to control inflammation.
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Asthma
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Safer and more affordable medicine for all? How pharmacogenomics may level the playing field
Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
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Asthma patient genetic analyses reveals glucocorticoid resistance mutation
A genetic analysis has shown that a mutation in the HSD3B1 gene is connected to glucocorticoid treatment resistance in patients with severe asthma.
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Protein vital for enterovirus replication identified by study
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
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Researchers discover bronchospasms mechanisms using microdevice
A ‘bronchi-on-a-chip’ has been created by researchers to identify the processes of bronchospasms which could aid in respiratory disease therapies.
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Integrated multi-‘omic’ studies could lead to precision treatment for asthma
Researchers say integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients.
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Study reveals vulnerability of common pathogenic viruses
Researchers have developed a stabilisation technique for widespread viruses, creating drug opportunity.
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Researchers take a leap forward for new anti-inflammatory drugs
Treatments for chronic inflammatory diseases are one step closer as a new study discovers a way to stop inflammation in its tracks.
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Targeted oral treatments for severe asthma
Researchers are aiming to identify whether antibiotics could be used to treat severe asthma in place of steroids which often have unwanted side effects...
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Kidney disease biomarker could help detect COPD
A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...
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Scientists find that dectin-1 receptor protects against allergies
Contrary to previous notions that the receptor dectin-1 causes allergic reactions, new research from the John Hopkins Bloomberg School of Public Health has found that it actually prevents this response, indicating new targets for allergy and asthma drugs.
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MiR-223 could help treat cancer and asthma
A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer...
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Immune signature predicts asthma susceptibility
Researchers have identified a subset of T cells, whose frequency serves as early childhood immune signature that predicts the risk of developing asthma later on.
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Asthma biomarkers identified from lung bacteria
New research suggests that the lung microbiome plays a significant role in asthma severity and response to treatment...
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Research reveals antibody treatment pathway for severe allergic asthma
Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...