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New DNA aptamer stabilises atherosclerosis plaques
The nucleic acid drug, iSN04, could have applications for pathological angiogenesis involved in atherosclerosis, cancer, and retinopathy.
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Atherosclerosis
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Werner syndrome: mechanism behind atherosclerosis elucidated
Researchers have developed a new in vitro co-culture system which enables an in-depth molecular analysis of atherosclerosis.
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Anti-cancer drugs could treat or prevent atherosclerosis
Researchers discovered that smooth muscle cells can change into cancer-like cell types and worsen atherosclerosis.
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4PY found to directly trigger vascular inflammation
Researchers have discovered a new pathway which seems to be a significant contributor to the development of cardiovascular disease.
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Improving treatments for rheumatoid arthritis patients
Researchers found that resolvinT4 restores protective macrophage biological activities in rheumatoid arthritis patients.
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Biological robots: a new therapeutic tool
Anthrobots derived from human tracheal cells could perform therapeutic work without initiating an immune response.
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Investigating heart disease through arterial calcification and repair mechanisms
Professor at Texas Tech University's Department of Biological Sciences has been granted an Innovative Project Award by the American Heart Association to delve into the intricacies of atherosclerosis, a condition responsible for artery thickening and severe health complications.
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Gut bacteria linked to fatty deposits in heart arteries
Swedish study reveals a significant link between specific gut bacteria and the development of coronary atherosclerotic plaques, a leading cause of heart attacks.
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New findings may lead to cardiovascular disease treatment
New research has found that immune cells produce a chemical messenger that prevents heart disease–related inflammation
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Targeted nanomedicine reduces vascular lesions in mouse models
The new nanoparticle uses a peptide to target the vascular cell adhesion molecule 1 and reduced the size of vascular lesions in a mouse study.
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Scientists discover new clue for platelet activation to target thrombosis
Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.
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The potential of epigenomic medicine in cardiology
Advances in genomic medicine are playing an increasingly important role in the field of cardiology. Better analysis and understanding of patient genomic and epigenomic information can enable more personalised patient treatment and medical intervention. Here, Professor John Giannios considers the potential to use genomic medicine to prevent, monitor, diagnose and…
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Drugs with potential to stop plaque build-up in arteries identified
A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
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Synthetic peptides block atherosclerosis in pre-clinical studies
Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
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Inhibiting the GLS1 enzyme could improve numerous age-associated disorders, finds study
In a new study, inhibitors of the GLS1 enzyme caused the death of senescent cells and relieved the symptoms of various age-related diseases in mice.