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Atherosclerosis

news

New DNA aptamer stabilises atherosclerosis plaques

30 August 2024 | By Drug Target Review

The nucleic acid drug, iSN04, could have applications for pathological angiogenesis involved in atherosclerosis, cancer, and retinopathy.

news

Werner syndrome: mechanism behind atherosclerosis elucidated

13 June 2024 | By Drug Target Review

Researchers have developed a new in vitro co-culture system which enables an in-depth molecular analysis of atherosclerosis.

news

Anti-cancer drugs could treat or prevent atherosclerosis

2 May 2024 | By Drug Target Review

Researchers discovered that smooth muscle cells can change into cancer-like cell types and worsen atherosclerosis.

news

4PY found to directly trigger vascular inflammation

21 February 2024 | By Drug Target Review

Researchers have discovered a new pathway which seems to be a significant contributor to the development of cardiovascular disease.

news

Improving treatments for rheumatoid arthritis patients

7 February 2024 | By Drug Target Review

Researchers found that resolvinT4 restores protective macrophage biological activities in rheumatoid arthritis patients.

article

Biological robots: a new therapeutic tool

9 January 2024 | By Ellen Capon (Drug Target Review)

Anthrobots derived from human tracheal cells could perform therapeutic work without initiating an immune response.

heart disease, Human,Heart,With,Blood,Vessels.,3d,Illustration

news

Investigating heart disease through arterial calcification and repair mechanisms

19 July 2023 | By Izzy Wood (Drug Target Review)

Professor at Texas Tech University's Department of Biological Sciences has been granted an Innovative Project Award by the American Heart Association to delve into the intricacies of atherosclerosis, a condition responsible for artery thickening and severe health complications.

gut `bacteriaMicrobiome,Intestine,Factories,And,Microbiota.,Gut,Health,3d,Render.,Microvilli

news

Gut bacteria linked to fatty deposits in heart arteries

12 July 2023 | By Izzy Wood (Drug Target Review)

Swedish study reveals a significant link between specific gut bacteria and the development of coronary atherosclerotic plaques, a leading cause of heart attacks.

Image showing Human body, heart and vascular system. The circulation of blood in the body.3d illustration

news

New findings may lead to cardiovascular disease treatment

31 March 2022 | By Ria Kakkad (Drug Target Review)

New research has found that immune cells produce a chemical messenger that prevents heart disease–related inflammation

news

Targeted nanomedicine reduces vascular lesions in mouse models

7 December 2021 | By Anna Begley (Drug Target Review)

The new nanoparticle uses a peptide to target the vascular cell adhesion molecule 1 and reduced the size of vascular lesions in a mouse study.

Illustration of blood clot with man holding chest in the background

news

Scientists discover new clue for platelet activation to target thrombosis

23 August 2021 | By Anna Begley (Drug Target Review)

Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.

article

The potential of epigenomic medicine in cardiology

22 June 2021 | By Professor John Giannios (Learna)

Advances in genomic medicine are playing an increasingly important role in the field of cardiology. Better analysis and understanding of patient genomic and epigenomic information can enable more personalised patient treatment and medical intervention. Here, Professor John Giannios considers the potential to use genomic medicine to prevent, monitor, diagnose and…

news

Drugs with potential to stop plaque build-up in arteries identified

26 February 2021 | By Victoria Rees (Drug Target Review)

A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.

news

Synthetic peptides block atherosclerosis in pre-clinical studies

15 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.

close up of an old person's hands holding a walking stick - idea of age-related diseases/disorders

news

Inhibiting the GLS1 enzyme could improve numerous age-associated disorders, finds study

5 February 2021 | By Hannah Balfour (Drug Target Review)

In a new study, inhibitors of the GLS1 enzyme caused the death of senescent cells and relieved the symptoms of various age-related diseases in mice.

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Atherosclerosis