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Bipolar disorder

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Five HERV expression signatures linked to psychiatric disorders

23 May 2024 | By Drug Target Review

This is the first study to demonstrate that a specific set of HERVs expressed in the human brain contribute to disorders like schizophrenia.

article

Safer and more affordable medicine for all? How pharmacogenomics may level the playing field

16 March 2020 | By Drug Target Review

Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.

news

Cryo-EM shows structure of TRPM2

25 September 2018 | By Iqra Farooq (Drug Target Review)

The structure of the protein TRPM2, a possible drug target, has been revealed for the first time by researchers at Van Andel Research Institute...

news

ANT1 mutation links bipolar disorder to mitochondrial disease

12 June 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have reported that mitochondrial dysfunction affects the activity of serotonergic neurons in mice with mutations of ANT1...

news

DRD2 crystal structure provides antipsychotic drug development tool

26 January 2018 | By Dr Zara Kassam (Drug Target Review)

Crystal structure of the dopamine 2 receptor bound to an antipsychotic drug provides a much-needed discovery in the quest to create effective drugs with fewer side effects...

news

New genes identified in children linked to stress & bipolar disorder

9 May 2017 | By Niamh Marriott (Drug Target Review)

Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a new study...

Researchers create a roadmap of bipolar disorder

news

Researchers create a roadmap of bipolar disorder and how it affects the brain

4 May 2017 | By Sarah Wills (Drug Target Review)

Global study reveals thinning of gray matter in brain regions responsible for inhibition and emotion

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Recommended

Bipolar disorder

Five HERV expression signatures linked to psychiatric disorders

Safer and more affordable medicine for all? How pharmacogenomics may level the playing field

Cryo-EM shows structure of TRPM2

ANT1 mutation links bipolar disorder to mitochondrial disease

DRD2 crystal structure provides antipsychotic drug development tool

New genes identified in children linked to stress & bipolar disorder

Researchers create a roadmap of bipolar disorder and how it affects the brain