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Non-coding RNA helps suppress breast cancer
2 February 2016 | By Victoria White
A team of scientists from Bath, Cambridge and the USA has identified a piece of non-coding RNA that stops cells turning cancerous...
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Breast cancer
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Breast cancer study reveals new drug targets and combinations
19 January 2016 | By Victoria White
The largest analysis of breast cancer cell function to date suggests dozens of new uses for existing drugs, new targets for drug discovery, and new drug combinations...
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Tiziana Life Sciences to drive its first-in-class Bcl-3 inhibitor
8 January 2016 | By Victoria White
The first-in-class candidate, CB1, has shown potent anti-metastatic activity, and with an impressive in vivo efficacy and safety profile...
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Drug generates exciting results in metastatic breast cancer models
23 December 2015 | By Victoria White
A team at CSHL has announced preclinical data suggesting the promise of a novel drug directed against a novel target in malignant mammary tumours...
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ICR identify Brf2 as a potential target for future cancer drugs
4 December 2015 | By Victoria White
ICR scientists have discovered Brf2 acts as a ‘master switch’ within cancer cells that seems to override the normal stress response...
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Oncology therapeutic pipeline boasts over 6,000 products
2 December 2015 | By Victoria White
GBI Research states that the majority of oncology therapeutics are in the early stages of the pipeline, with 2,937 at the Preclinical stage and 1,591 at the discovery stage...
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Scientists successfully combine antibody-drug conjugates with immunotherapy
26 November 2015 | By Victoria White
Researchers from the University of Basel have, for the first time, successfully combined an antibody-drug conjugate with a therapy that stimulates the immune system to attack breast cancer cells...
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Evgen expands pipeline with novel compounds
23 November 2015 | By Victoria White
Evgen has said it will use its Sulforadex platform to synthesise and stabilise the newly acquired compounds with a view to taking the most promising into clinical development...
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Super natural killer cells destroy lymph node cancer cells and halt metastases
13 November 2015 | By Victoria White
The engineered cells induce apoptosis, where the cancer cells self-destruct and disintegrate, preventing the lymphatic spread of cancer any further...
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Hercules receives Eurostars grant to develop CB7993113 for breast cancer
3 November 2015 | By Victoria White
Hercules has said that the Eurostars grant will enable the company to advance CB7993113 through preclinical development towards clinical trials in patients with triple negative breast cancer...
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Scripps scientists make leukaemia cells kill each other
20 October 2015 | By Victoria White
The surprise finding could lead to a powerful new therapy for leukaemia and possibly other cancers...
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Breast cancer vaccine OQR200 completes proof-of-concept study
15 October 2015 | By Victoria White
In the study, the vaccine elicited the expression of very high levels of polyclonal antibodies targeting multiple epitopes on Her2/neu...
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Tamoxifen beats MRSA superbug in mice models
13 October 2015 | By Victoria White
Researchers have found that tamoxifen gives white blood cells a boost, better enabling them to respond to and kill bacteria in laboratory experiments...
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Cancer Research UK launches the Grand Challenge to help beat cancer
12 October 2015 | By Victoria White
International scientists across all disciplines are invited to come up with solutions to seven challenges which cover some of the most important unanswered questions in cancer research...
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3SBio enters licensing deal for antibody-drug conjugate ALT-P7
12 October 2015 | By Victoria White
Preclinical proof-of-concept has demonstrated superiority of ALT-P7 over current drugs in murine models of HER2-positive breast cancer...