news Novel ‘prodrug’ designed to eliminate cancer without harming healthy cells 23 November 2022 | By Izzy Wood (Drug Target Review) US researchers discovered in a study in mice that augmented drug eliminates cancer cells without causing toxicity.
news Bacteria in a tumour’s microbiome could influence how cancer responds to treatment 23 November 2022 | By Izzy Wood (Drug Target Review) US researchers find that bacteria could help tumours progress and resist treatment.
news New MACHETE technique developed to slice into cancer genome 21 November 2022 | By Izzy Wood (Drug Target Review) Sloan Kettering Institute (SKI) researchers have developed a new machete technique to slice into the cancer genome and study copy number alterations.
news First use of CRISPR to substitute genes for cancer treatment 16 November 2022 | By Izzy Wood (Drug Target Review) US scientists, using CRISPR technology, removed specific genes in humans to allow the immune system to be more activated against cancer.
news Peptides with anticancer potential discovered in new study 15 November 2022 | By Victoria Rees (Drug Target Review) Researchers have found peptides that bind to chains of ubiquitin proteins in cancer cells, suggesting they could be used as a therapeutic strategy.
news Novel CAR T screens identify most effective cancer immunotherapy cells 11 November 2022 | By Ria Kakkad (Drug Target Review) Researchers have developed a new method for comparing CAR T cells, each with slightly different molecular features, to determine which is most effective and long-lasting against cancer.
news Nanotechnology platform sensitises cancer to immunotherapy 11 November 2022 | By Victoria Rees (Drug Target Review) A new pre-clinical study has utilised nanoparticles to attach immune-activating molecules to cancer cells.
news Experimental cancer vaccine shows promise in animal studies 11 November 2022 | By Victoria Rees (Drug Target Review) NIH researchers who intravenously delivered a cancer vaccine to mice report that it increased the number of T cells able to combat tumours.
news Metastatic potential of cancer cells increased in high viscosity environments 4 November 2022 | By Izzy Wood (Drug Target Review) UPF and John Hopkins scientists have discovered how cancer cells exposed to high viscosity environments change their movements to improve their invasiveness and favour metastases.
news Vitamin C improves immunogenic properties of dendritic cells, study shows 4 November 2022 | By Izzy Wood (Drug Target Review) Spanish researchers have discovered that vitamin C may hold the key to improving the efficacy of dendritic cell-derived anticancer therapies.
news RNA: the key to cancer research? 2 November 2022 | By Izzy Wood (Drug Target Review) In the production of RNA, researchers in Spain and Denmark have found a method for attacking cancer cells.
news Newly discovered GPCR signalling process opens possibility for novel therapies 28 October 2022 | By Izzy Wood (Drug Target Review) US researchers have found that G protein-coupled receptors function in a way not previously known, which suggests untapped potential.
news New method to label proteins could help track disease 26 October 2022 | By Ria Kakkad (Drug Target Review) Scientists have developed a new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer.
news Researcher develops nanoelectronics for personalised immunotherapies 21 October 2022 | By Ria Kakkad (Drug Target Review) Dr Larysa Baraban, physicist at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is researching a chip that should ultimately make it possible to develop personalised cancer immunotherapies.
news Novel approach developed to deliver cancer immunotherapy drug 21 October 2022 | By Izzy Wood (Drug Target Review) Researchers have eradicated malignant tumours in mice by combining an immunotherapy agent with a molecular delivery system that targets tumour acidity.
