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Cellular ‘waste product’ could enhance cancer immunotherapy, study shows
A new study has shown that lactate, a metabolic byproduct produced during exercise, could augment current cancer immunotherapies.
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RASA2 gene make T cells more resilient
New study finds that using CRISPR to block RASA2 gene makes T cells more resilient against cancer.
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New method by which T cells can react to lower doses of antigens
Researchers have discovered a way to ignite T cells, potentially increasing the scope and success of T cell-based immunotherapy.
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Combining immunotherapy and virotherapy shows promise for treatment-resistant cancers
The study describes how oncolytic virotherapy can work with existing immunotherapy techniques, boosting the immune capacity to effectively target and destroy cancer cells.
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Researchers develop a small molecule that makes immunotherapy available to all cancer patients
Scientists have identified and synthesised a small molecule that could be a more accessible and affective alternative to an antibody that treats a wide range of cancers.
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A new 3D tool for measuring intracellular lipid droplets
Researchers have developed a novel label-free method named tomographic phase microscopy in flow cytometry for measuring intracellular lipid droplets in 3D.
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A new study has highlighted how an antibody strengthens bonds between cells
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
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Takeda enters agreement with F-star Therapeutics to license bispecific antibody
F-star Therapeutics has announced a licence agreement with Takeda for a novel next-generation immuno-oncology bispecific antibody.
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Research shows that EBAG9 leads to strengthened immune response to cancer
The scientists say that shutting down the EBAG9 gene allows the body to destroy tumour cells earlier and more radically.
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New discovery in cancer progression paves way to combat the disease
Researchers have identified an important gene that could enable more targeted treatment for cancer.
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Discovered receptor that could alleviate the need for chemotherapy
Researchers have shown that a synthetic IL-9 receptor allows T cells to fight against cancer without the need for chemotherapy or radiation.
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New insight into the key properties of an antibody needed to fight cancer
The findings have enabled researchers to design antibodies to activate important receptors on immune cells and deliver more powerful anti-cancer effects.
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How EGF receptors influence cell growth
A new insight into the way the EGF receptor sends signals into cells could help researchers design new cancer drugs that target this protein.
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Whole genome sequencing in cancer research
A recent whole genome sequencing study has revealed hidden insights into the causes of cancer. In an exclusive article, Dr Andrea Degasperi from the Early Cancer Institute at the University of Cambridge, UK spoke to Drug Target Review's Ria Kakkad about the study's implications and the future of whole genome sequencing.
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Human urine-derived stem cells have robust regenerative potential
A new study provides the possibility to evaluate the capacity of telomerase-positive human urine-derived stem cells to become a wide variety of other cell types.
