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New cancer treatment regimens could be identified with novel technology
A new technology called mass cytometry, or CyTOF, is providing new insights into a range of key proteins in blood cancer cells.
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Artificial binding protein could be developed into a novel anti-viral or cancer therapy
Scientists have created an artificial protein able to recognise and bind cell surface carbohydrates with high affinity and selectivity.
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Drug candidate stops tumour growth with little toxicity in mice
A star-shaped molecule along with a modified platinum drug have demonstrated success at combatting tumours with few toxic effects in mice.
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New drug discovery centre with screening capabilities opens in Australia
The National Drug Discovery Centre (NDDC) has opened in Australia, with support from the government to subsidise the screening of medicinal compounds.
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Ru-Pt conjugate drug could be the future for cancer therapies
Researchers combined cisplatin, an enhancer and a photodynamic therapy (PDT) drug into a single conjugate that had 10 times the efficacy in treating treatment resistant cancer cells.
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Safer and more affordable medicine for all? How pharmacogenomics may level the playing field
Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
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Increasing ion channel function in cancer T cells could be new immunotherapy
Researchers have found that there is less calmodulin binding to ion channels in the T cells from cancer patients, presenting a new immunotherapeutic target.
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Structure of commonly mutated histone chaperone revealed by new study
Researchers have shown how ATAD2, a histone chaperone protein, may load histones on to DNA in order to create the chromatin structure.
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TEX264 protein could be targeted to help protect DNA from damage
Scientists have identified that the TEX264 protein and associated enzymes protect the genome from damage, which could lead to new anti-ageing and neurodegeneration therapies.
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Researchers identify enzyme critical for regulating cell signalling
An enzyme that adds a cell-signalling code to proteins has been identified by researchers, who say their discovery could aid in the development of cancer therapies.
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3D forces exerted by tiny cell clusters revealed through new technique
A new imaging technique, which has revealed 3D forces exerted by tiny cell clusters, could help scientists understand how tissue forms, how wounds heal or how tumours spread.
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Mitochondria-boosting compound promotes immunotherapy in mice
Researchers have discovered that a small molecule can help some T cells combat tumours during PD-1 blockade immunotherapy in mice.
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Researchers find drug improves cancer immunotherapy in mice
A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.
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Stainless imaging developed by adding infrared to standard microscopes
A new method to image cancerous tissues has been created by researchers who have paired infrared measurements with high-resolution optical images.
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Researchers generate atlas of thymus to understand T-cell development
A new study has created an atlas of human thymus development, to reveal which genes are needed for the production of specific T cells.
