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‘Ubiquitin clipping’ proteomics technique could be used as novel treatment
A new technique called ‘ubiquitin clipping’ has been created which could aid proteomics research and the development of new drugs for ubiquitination.
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Cancer
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Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
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Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
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Study reveals cancer cell fuelling mechanism
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
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Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
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Newly discovered signal could lead to anti-cancer therapies
Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.
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Study of TP53 mutations shows insight into the gene’s function
New study sheds light on how the TP53 gene becomes mutated and how those mutations can help predict clinical outlooks for cancer.
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Study discovers key process in the cause of cell aging
Researchers have identified a key process behind senescence, or why cells age, which could be used to improve treatments for cancer.
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Scientists control living cells using artificial protein switch
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
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Method for inhibiting tumour growth enzyme discovered
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
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Experimental compound slows blood cancer growth
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
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Study identifies protein key to successful chemotherapy
A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
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Gene discovered to play key role in cancer metastasis
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
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Vaccine strategy devised to boost T-cell therapy
A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.