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Study discovers key process in the cause of cell aging
Researchers have identified a key process behind senescence, or why cells age, which could be used to improve treatments for cancer.
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Scientists control living cells using artificial protein switch
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
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Study finds fat cells play key role in melanoma metastasis
Researchers have found that fat cells transfer cytokines to melanoma cells, which transforms them into aggressive tumours, indicating a drug target for the condition.
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Method for inhibiting tumour growth enzyme discovered
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
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Experimental compound slows blood cancer growth
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
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Study identifies protein key to successful chemotherapy
A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
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Gene discovered to play key role in cancer metastasis
A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
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Vaccine strategy devised to boost T-cell therapy
A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.
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New evidence shows cytotoxic T cells can destroy targets of large mass
New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
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Five latest developments for models
The use of models is a key feature of preclinical studies and in recent months there have been several new advancements in this area. This article investigates five of the latest developments.
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Secondary structures study could lead to making cancer cells vulnerable
Researchers have used machine learning to discover that the two most widespread DNA structures cause genome mutations that lead to cancer.
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Discovering new routes to cancer drug discovery with neutrons
From the world’s flagship neutron science facility, Institut Laue-Langevin (ILL), Matthew Blakeley shares insights into how they are harnessing the power of neutrons to aid their search for new cancer treatments.
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Study identifies protein pathway key in cancer growth
Researchers have discovered a pathway which when blocked can cause cancer cell death, pointing to new therapies.
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Study reveals antioxidant role in spread of lung cancer
Researchers have discovered that lung cancer cells metastasise using antioxidants, informing potential future therapies.
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Potential drug target for Alzheimer’s identified
New research has identified an enzyme which causes degradation of dendritic spines, pointing to a drug target for Alzheimer’s.
