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Researchers identify chemotherapy-enhancing molecule
A new study has found a small molecule which prevents cancer cells from mutating and becoming resistant to chemotherapy.
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New link shown between innate immune sensing and cellular senescence
Scientists have discovered a cell intrinsic tumour suppressor role of the innate immune sensor Toll-like receptor 2.
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Protein discovery leads to new hyperparathyroidism drug target
A new signalling protein discovery could lead to drug-based therapies to treat hyperparathyroidism.
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Molecule found to boost immune cells leads to new cancer therapy target
A study has identified a molecule which boosts immune cell function and could be used in cancer therapies.
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Update on the development of new novel cancer immunotherapy
The SCIB2 vaccine is to to be administered using new nanoparticle formulation in planned Phase 1/2 clinical trial.
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Gene editing tools market valued at $258 million in 2018
The global gene editing tools market is estimated to have accounted for more than US$258 million in terms of value in 2018.
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Tissue-damaging protein channel identified
Researchers have discovered an acid-activated protein which could stop damage to tissues as a result of stroke and other health issues.
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New approach to targeting cancer cells developed by researchers
A new approach to targeting cancer cells that circumvents a challenge faced by currently available cancer drugs has been developed.
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New technique enables detailed genetic analysis of cancer cells
A new way to cleanly separate out cancer cells from a blood sample will enable comprehensive genetic profiling of the cancer cells.
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Squaring the circle – cancer vaccines
By the 1890s William B. Coley had injected streptococcal organisms in patients with solid tumours (“Coley’s Toxins”) to activate the immune system. Coley (1862-1936) was an American bone surgeon and pioneer of cancer immunotherapy. He was convinced that post-surgical infections had helped patients to recover better from their cancer by…
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WINTHER trial yields promising results
Comprehensive tumour profiling promises new therapeutic options for patients with advanced cancer.
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New technique developed to expand multimodal single cell analysis
A new technique, called ECCITE-seq, has been developed to allow researchers to perform high-throughput measurements of multiple modalities of information from single cells.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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Gut microbiome directs immune system to fight cancer
The advent of immune checkpoint inhibitors is a major breakthrough in cancer immunotherapy...
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Heating up tumours could make CAR T therapy more effective
When a heating technique called photothermal ablation was combined with the infusion of CAR T cells, it suppressed melanoma tumour growth for up to 20 days in mice...