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Ubiquilin-4 biomarker links cancer progression to genome instability
High level of specific protein in tumours indicates prognosis as well as optimal treatments...
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Stem cell study optimises bone marrow transplants
A study has shown how stem cells that are transplanted act in a different way to those ordinarily present, without a transplant...
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Drug sponge could minimise effects of cancer therapy
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
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‘Activating’ the immune system against cancer
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
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Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
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Using machine learning to predict symptoms
Machine learning could, in future, be the way that clinicians decide on particular courses of treatments for patients affected by cancer...
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Computational advances in the label-free quantification of cancer proteomics data
Proteomics research has become a popular method for characterising functional proteins as well as discovering the innovative targets for oncologic disorders...
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DNA barcodes that reliably work: A game-changer for biomedical research
A new method for correcting the errors that creep into DNA barcodes has paved the way for more ambitious medical research...
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Calcium carbonate sprayable gel could fight cancer
A sprayable gel containing calcium carbonate nanoparticles with an antibody specifically targeted to block CD47, could be the future of cancer treatments...
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Phospholipid reactive T-cells could play a role in cancer
Phospholipid-reactive T-cells that are able to recognise phospholipids could help in treatments against cancer, autoimmune diseases and dyslipidemia...
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Pinpointing biopsies to detect and target cancer
Software that overlays tumour information from MRI scans onto ultrasound images could help to highlight areas of concern, and to detect and target cancer...
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Frizzled receptors could be drug targets for treating major diseases
Frizzled receptors, from the GPCR family, could soon be a target to treat numerous diseases such as cancer, fibrosis and CVD...
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New approach turns immune cells into tiny anti-tumour drug factories
In lab and mouse experiments researchers have developed a method to leverage B cells to manufacture and secrete tumour-suppressing microRNAs...
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Self-delivering RNAi: paving the way for a new class of cancer immunotherapies
Earlier this year, the National Cancer Institute published its annual report to the nation on the status of cancer stating that there will be nearly 1.8 million new cases of cancer in 2018.1 New therapies have developed over time to improve cancer patient outcomes, including antibody immunotherapies targeting immune checkpoints,…
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Targeting innate immunity to treat disease: potential therapeutic applications
Despite being one of the more ancient aspects of immunity, therapeutic modulation of the innate immune system has rarely been attempted. Innate immunity is intrinsically linked to the generation of inflammation – necessary for signalling to the adaptive immune system but often self-perpetuating and over-exaggerated, leading to deleterious effects, including…