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Calcium carbonate sprayable gel could fight cancer
A sprayable gel containing calcium carbonate nanoparticles with an antibody specifically targeted to block CD47, could be the future of cancer treatments...
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Phospholipid reactive T-cells could play a role in cancer
Phospholipid-reactive T-cells that are able to recognise phospholipids could help in treatments against cancer, autoimmune diseases and dyslipidemia...
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Pinpointing biopsies to detect and target cancer
Software that overlays tumour information from MRI scans onto ultrasound images could help to highlight areas of concern, and to detect and target cancer...
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Frizzled receptors could be drug targets for treating major diseases
Frizzled receptors, from the GPCR family, could soon be a target to treat numerous diseases such as cancer, fibrosis and CVD...
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New approach turns immune cells into tiny anti-tumour drug factories
In lab and mouse experiments researchers have developed a method to leverage B cells to manufacture and secrete tumour-suppressing microRNAs...
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Self-delivering RNAi: paving the way for a new class of cancer immunotherapies
Earlier this year, the National Cancer Institute published its annual report to the nation on the status of cancer stating that there will be nearly 1.8 million new cases of cancer in 2018.1 New therapies have developed over time to improve cancer patient outcomes, including antibody immunotherapies targeting immune checkpoints,…
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Targeting innate immunity to treat disease: potential therapeutic applications
Despite being one of the more ancient aspects of immunity, therapeutic modulation of the innate immune system has rarely been attempted. Innate immunity is intrinsically linked to the generation of inflammation – necessary for signalling to the adaptive immune system but often self-perpetuating and over-exaggerated, leading to deleterious effects, including…
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High-throughput platform could map cancer drug target activity
Manchester University researchers have developed a high-throughput platform to analyse and study a family of enzymes that are linked to cancer...
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Stopping cancer cells in their tumour ‘highways’
Using controlled network microenvironments, tumour cells were prevented from travelling, which could prevent spread of the cancer throughout the body...
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War On Cancer 2018: targeted therapies in oncology
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
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New technique to simultaneously target fibroblasts while killing cancer cells
Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells...
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Using anti-malaria drugs to slow tumour growth
Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...
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Defective damage repair to DNA results in chromosome chaos
German researchers have shown how defective damage repair to DNA results in chromothripsis - clustered chromosomal rearrangements...
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CRISPR used to prevent cancers tied to EBV and KSHV
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...
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Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
