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Preventing exhaustion in immune cells boosts immunotherapy in mice
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
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Staphylococcus epidermidis may protect against skin cancer
Researchers have reported a potential new role for some bacteria on the skin, protecting against cancer...
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GAPSA reveals new HIV targets
Researchers have developed the first-ever high-throughput, genome-scale imaging-based approach to investigate protein stability...
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Five genetic changes linked to pancreatic cancer risk
Researchers have discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer...
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MiR-223 could help treat cancer and asthma
A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer...
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Flexible warped nanographene developed for bioimaging
An international team of scientists has developed a water-soluble “warped nanographene”, a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging.
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Lipid asymmetry plays key role in activating immune cells
Researchers have shown that by preventing loss of membrane asymmetry it's possible to control the immune response...
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Studying mitosis’ structure to understand the inside of cancer cells
Researchers have uncovered the architecture of the spindle pole body in yeast...
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iPS cells could serve as an effective cancer vaccine
A study in mice has suggested that iPS cells may train the immune system to attack or even prevent tumours...
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Metabolomics heralded as encouraging tool for personalised treatment of cancer
Researchers in Spain provide specific examples of metabolomics applications in the field of clinical pharmacology and precision medicine, focusing on the therapeutic management of cancer.
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New machine learning algorithm uncovers time-delayed interactions in cells
Scientists have designed a new machine learning algorithm that uses time-series data to uncover underlying biological networks.
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Novel classification can lead to new ways to diagnose and treat cancer
A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumour growth.
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Huntington’s disease provides new cancer weapon
Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...
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cDC1 cells could improve cancer immunotherapy
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...
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DNMT3A crystal structure linked to cancer development
Scientists offer important information for understanding de novo DNA methlylation...