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Pixelated gene expression tool provides fast accurate results for RNA analysis
Researchers have demonstrated how a pixelated gene expression tool can accurately measure RNA levels more quickly than existing methods allow.
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New study suggests possible marker to test patient immunotherapy benefit
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments.
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EXD2 enzyme identified as key player in mitochondrial protein synthesis
A team of researchers led by IRB Barcelona in Spain have identified a key function of the enzyme EXD2 as being the maintenance of protein production in the mitochondria.
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Researchers develop a remote-controlled cancer immunotherapy system
Researchers have developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognise and kill cancer cells.
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Discovery into cells’ energy supply could lead to targeted cancer treatment
Scientists have made a significant breakthrough in understanding how the molecular machines that produce key proteins are cleaned and maintained. ..
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APC-mimetic scaffolds could facilitate more effective precision immunotherapies
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
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Human protein may aid neuron invasion by virus that causes hand, foot, and mouth disease
A human protein known as prohibitin may play a significant role in infection of the nervous system by EV71, one of several viruses that can cause hand, foot, and mouth disease.
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NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
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Industry-academic collaboration results in improved understanding of cancer cell regulation
A team of researchers from the University of Liverpool and AstraZeneca has made an important contribution to our understanding of cancer cell regulation, holding promise for improved future cancer treatment.
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Researchers use AI technology to chart immune cell receptor
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical ‘antennas’ on the surface of immune system T-cells.
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Near-infrared molecular imaging identifies lung nodules for resection in osteosarcoma
In a proof-of-principle case report, researchers announce that targeted fluorescence successfully identified pulmonary metastases in a patient with osteosarcoma...
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Mechanism identified of impaired dendritic cell function that weakens response to cancer
New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...
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F50/T50 combination provides artificial ovary prototype
A protein formulation based on fibrin resembles the architecture and rigidity of human ovarian tissue and could be used for ovary transplant...
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Proteogenomics research – on the frontier of precision medicine
Proteogenomics is the systematic and comprehensive integration of proteomics with genomics and transcriptomics. Proteogenomics is opening new hallmarks in biomedical research. Recently, several studies have demonstrated the relevance of proteogenomics in cancer research. This article provides a brief review of the advantages of proteogenomics in precision medicine.
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Using 3D cell cultures to fight anti-cancer therapy resistance
An international team of researchers have developed 3D cell cultures in which genes can be specifically modified to improve the use of targeted anti-cancer drugs...
