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SOPHiA artificial intelligence empowers liquid biopsies to fight cancer
Sophia Genetics injects artificial intelligence in liquid biopsies to accelerate early detection of cancer and monitor treatments’ effectiveness.
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Cancer
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Attacking metastatic tumours in the brain
Targeting HER3 could cripple metastatic cancers that have spread to the brain...
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Screening In-Depth Focus 2017
Included in this Screening In-Depth Focus: Phenotypic and target-based screening; Killing cancer cells using clinical drug resistance; Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool...
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Flexible new method for early cancer diagnosis
Investments are now being made to roll out this innovation across healthcare and broaden the scope of the research in this field.
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Anticancer nanomaterials created by simulating underwater volcanoes
Researchers at Aalto University, Finland, have developed anticancer nanomaterials by simulating the volcano-induced dynamic chemistry of the deep ocean.
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New counterintuitive approach to treating brain cancer
The loss of the tumour suppressor gene PTEN has been linked to tumour growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM).
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New cell separator could advance cancer and Alzheimer’s research
A new cell separator that began life as a tinfoil and epoxy glue prototype built with supplies from a University shop could revolutionise stem-cell and regenerative cell-based therapies.
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Cancer-causing virus masters cell’s replication & immortality
Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated 9/10 humans without causing any ill effects. That is, until this virus causes mononucleosis…
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PET/CT helps predict therapy effectiveness in paediatric brain tumours
Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.
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Tracking unstable chromosomes helps predict lung cancer’s return
Scientists have found that unstable chromosomes within lung tumours increases the risk of cancer returning after surgery, and have used this new knowledge to detect relapse long before standard testing.
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£2.5 million Cancer Research UK collaboration to target ‘undruggable’ RAS
Scientists will develop and test promising new molecules for targeting RAS, one of the most common driving mutations in aggressive, hard to treat cancers including pancreatic and lung cancer.
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Diagnosing cancer: new process for identifying biomarkers established
Scientists have established a process for identifying biomarkers for the diagnosis of different types of cancer.
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Aprea Therapeutics to collaborate with Memorial Sloan Kettering cancer center
Karolinska development's portfolio company Aprea Therapeutics, a privately held, clinical stage biopharmaceutical company developing novel anticancer therapies targeting the tumour suppressor protein p53, announced a collaboration with Memorial Sloan Kettering Cancer Center to study the effects of reactivation of tumour suppressor protein p53 by APR-246.
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A new role for an old immune cell may lead to novel therapies
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
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Antibodies In-Depth Focus 2017
Lone Friis and David Matthews discuss developability assessment of therapeutic antibodies, and Negin Mokhtari and colleagues explain nanoparticle-mediated enzyme delivery for application in cancer therapy...
