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Vitamin C effective at targeting cancer stem cells
Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to an article published in Oncotarget
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Cancer
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Towards systems biomarkers for cancer diagnosis
Cancer is asymptomatic during most of its pathogenesis. It is very difficult to see that a cancer is growing in a person, except for a few self-evident cases such as skin cancer. Its intangibility and year-, if not decade-long progression make cancer hard to diagnose until some symptoms warrant further…
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£100 million for Cancer Research’s ‘grand challenge’ competition winners
Cancer Research UK announced that four international teams are the first recipients of its global £100m Grand Challenge competition, which aims to overcome the biggest challenges facing cancer researchers in a global effort to beat cancer sooner.
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Amgen and Immatics to collaborate on bispecific cancer immunotherapies
The collaboration will combine Immatics’ Xpresident target discovery and T-cell receptor (TCR) capabilities with Amgen’s validated Bispecific T-cell Engager (BiTE) technology with the aim of creating novel oncology drugs.
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Macrophage raises £9 million & acquires immune-oncology technology
Macrophage Pharma, a newly formed immune-oncology company, has successfully raised £9 million in a Series A equity financing round.
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Immunotherapy and gene therapy combination shows promise against brain tumours
The outlook for brain tumour patients is pretty negative, with the median survival rate for patients with glioblastoma multiforme, or GBM, a mere 14.2 months.
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Nanohyperthermia softens tumours to improve treatment
The mechanical resistance of tumours and collateral damage of standard treatments often hinder efforts to defeat cancers.
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Industrialising organoids for the next generation of drug discovery
New synthetic 3D gel technology for cell culture promises to unlock the potential of ‘mini-organs’ for industrial drug discovery.
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QGel raises $12 million to grow mini-organs for drug discovery
The biomaterials company QGel has received $12 million to be used to accelerate QGel’s global expansion and broaden the company "organoids" products.
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Oncology collaboration: Proteros & MSD to find epigenetic target
22 November 2016 | By Niamh Louise Marriott, Digital Content Producer
Proteros has entered into a second research agreement with Merck aimed at developing small molecule compounds against an additional epigenetic target...
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Rural, poor and sick: The unseen cancer crisis in America
20 October 2016 | By Aaron Yao, PhD, University of Virginia School of Medicine
PhD student Aaron Yao highlights the shocking disparities between rural and urban eastern America and how the odds of cancer survival do not favour the impoverished...
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IL-34: a new target to tackle chemo-resistant cancer cells
3 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Researchers found that A549-DR was resistant to the chemotherapeutic drug when transplanted in mice, while A549-DR with depleted IL-34 became sensitive...
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‘Library’ of de-prioritised pharma compounds available for researchers
UK scientists can apply for MRC funding to use any of the compounds in medical research studies to investigate the underlying mechanics of disease...
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Infra-red light detects early signs of oesophageal cancer
6 September 2016 | By Niamh Louise Marriott, Digital Content Producer
Researchers sprayed a dye on oesophageal tissue samples taken from people with Barrett’s oesophagus – a condition that risk cancer development...
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New animal model will advance metastasic sarcomas research
30 August 2016 | By Niamh Louise Marriott, Digital Content Producer
Used for the first time as part of the team's latest work, the model may become a valuable experimental tool to analyse metastatic potential in sarcomas...
