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New biomarker advances cancer treatments
Researchers have discovered ways to enhance NIR-PIT to ensure tumours are treated sufficiently and improve patient outcomes.
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Machine could make CAR T-cell therapy more accessible
Researchers have developed a new bioreactor that can manufacture T cells faster than other technologies, which may advance immunotherapy.
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Key epitope can trigger tumour cell death
An epitope on CD95 receptor causes tumour cells to self-destruct and may prolong benefits of CAR T-cell therapy for solid tumours.
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Novel method for early cancer diagnosis
A recent scientific collaboration, led by the Institute of Nuclear Physics of the Polish Academy of Sciences, has overcome measurement challenges, enabling reliable cancer diagnosis.
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Human-derived proteins used in DREAM tool
CRISPR-DREAM tool used to activate insufficiently expressed genes and convert skin cells to induced pluripotent stem cells (iPSCs).
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Insights into the critical initial phase of embryonic development
Researchers from the University of Helsinki and the National Institutes of Health (NIH) in the United States have made a new discovery: the ectoderm, one of the germ layers, does not lose its pluripotency during gastrulation, contrary to prior beliefs.
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SRC-3: CoRegen’s revolutionary approach to cancer
Drug Target Review’s Taylor Mixides exclusively interviews David Lonard, PhD, Chief Scientific Officer at CoRegen and Associate Professor at Baylor University, to uncover the mechanisms of SRC-3 and why it’s key to targeting cancer – and only cancer.
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Childhood cancer survivors’ mortality risk
Researchers find genetic explanation for increased risk of developing second cancers.
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Proteolysis: new method developed to target cancer cells
Researchers have found that targeting chimeras with click-release proteolysis activates specific molecules that target cancer cells without harming health cells.
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Senescent immune cells promote lung tumour growth
A recent study sheds light on an unexpected discovery concerning macrophages, a vital type of white blood cell in the body's defence against infections and tumours.
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Novel approach to overcome resistance to cancer drugs
Researchers at the University of Queensland have discovered a promising drug target capable of addressing drug resistance and preventing tumour regrowth in cancer patients.
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Engineered immune cells for improved cancer defence
A collaborative team has uncovered a method to extend the functionality of CAR-T cells.
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Cancer inhibitors shows success in slowing tumour growth
Researchers have successfully demonstrated the potential of using a combination of inhibitors to effectively curb tumour growth and stave off relapses in patients afflicted with specific cancers.
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Bioengineered instrument reveals hidden cancer cells
Scientists at Stanford University have engineered a biomolecule that can specifically remove mucins from cancer cells. This breakthrough could have a significant impact on future cancer therapies.
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New research holds significance in regulating T cell function
New research shows T cells use the nuclear receptor RARα not just for gene regulation, but also to trigger cell surface events that activate them against pathogens and cancer.