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Cervical cancer

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Potential for targeted therapies based on the gigaxonin pathway

29 February 2024 | By Drug Target Review

Researchers have discovered that higher expression of gigaxonin suppresses aggressive growth of human head and neck cancer cells.

news

New algorithm can predict when cancer will resist chemotherapy

19 January 2024 | By Drug Target Review

The ML algorithm explores how genetic mutations collectively influence a tumour’s reaction to drugs impeding DNA replication.

news

Role of enzyme in tumour immune microenvironment identified

26 October 2023 | By Drug Target Review

Researchers have found that reducing glycosylation on the T cell surface may offer new approaches to cancer immunotherapy.

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Intratumoural bacteria drives radiation therapy resistance

23 October 2023 | By Drug Target Review

Lactate producing bacteria is responsible for rewiring metabolic signalling pathways, causing resistance to radiation therapy.

news

New test promises better detection of elusive cervical cancers

13 September 2023 | By Drug Target Review

Researchers have developed a novel test capable of detecting a form of cervical cancer that frequently eludes detection through traditional Pap tests.

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Researchers develop screening model to evaluate potential cervical cancer drugs

4 April 2023 | By Ria Kakkad (Drug Target Review)

Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.

Experimental cancer vaccine vial for immunization against Cancer disease. Doctor with vial of the Cancer vaaccine

article

Transforming the way cancer vaccines are designed and made

4 February 2023 | By Fraser Owen (Drug Target Review)

Researchers found that ‘rational vaccinology’ increases potency by changing the structural location of antigens and adjuvants.

news

Study highlights possibility of using 3D organoids of the cervix to test drugs

1 March 2022 | By Ria Kakkad (Drug Target Review)

A new study modelled chlamydia and HPV co-infection in patient-derived ectocervix organoids to reveal distinct cellular reprogramming.

news

“Ultrasensitive” HPV detection paves way for precision treatment

28 September 2021 | By Anna Begley (Drug Target Review)

A new study sequenced tumour DNA for the “ultrasensitive” detection of HPV, further honing precision treatment of the illness.

news

First patient-derived organoid model for cervical cancer developed

15 April 2021 | By Victoria Rees (Drug Target Review)

Novel organoid models of cervical cancer and a healthy human cervix have been developed to study the condition and its progression.

news

Cervical cancer cell-killing molecule manzamine A found in Indonesian sponge

6 April 2020 | By Victoria Rees (Drug Target Review)

A study has revealed that a sponge endemic to an Indonesian bay produces manzamine A, a compound which inhibits proteins in cervical cancers.

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Cervical cancer