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Novel nasal spray effectively prevents influenza infection
The nasal spray reduced influenza virus levels by >99.99 percent, which could safeguard public health if validated in humans.
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New trivalent vaccine for clade 1 sarbecoviruses
The vaccine provided complete protection with no detectable virus in the lungs and could be a routine part of people’s medical treatment.
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Beyond the lab: vaccine development
This report provides insights into current research and future prospects from potential breakthroughs to global collaboration in pandemic preparedness.
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How successive mRNA vaccines shape T-cell memory
A new study shows that changes in clonal dominance characterises T-cell memory against multiple COVID-19 variants following mRNA vaccinations.
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Serum biomarkers for COVID-19 identified
Proteins regulating plasminogen-plasmin levels can be used to identify patients at risk of progressing to a severe stage of COVID-19.
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The role of anti-viral drug development in a new pandemic era
As humanity faces an impending era of pandemics, global collaboration among governments, organisations and industry is critical. In this article, epidemiologist Dr Jay Varma explores the urgent need for researching and developing drugs to combat a range of epidemic-prone pathogens, and reflects on the increased risk of spillovers and the…
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Blocking the IL-6 receptor to protect tissues from CRS
The new study’s findings suggest that CRS can be treated with an IL-6 receptor antibody that has a short half-life.
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Breaking down barriers across the DMTA cycle
In this article, David Bardsley, Commercial Director, and Nick Foster, Vice President of Discovery CRO at Cresset, explore the challenges that occur when approaching drug discovery in silos and how harnessing advances in technology can help to overcome them.
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Explosive cell death: inflammation-causing gene
WEHI researchers have found that a genetic change of MLKL increases risk of uncontrolled inflammatory response
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COVID-19: rapid and reliable detection method
Commercially available mass spectrometers offer a reliable means of detecting the SARS-CoV-2 coronavirus.
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Research offers insight into swift spread of SARS-CoV-2 variants
Researchers have shown insights into the omicron variants of the SARS-CoV-2 virus, which have rapidly disseminated globally in the past year.
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Vaccine may reduce severity of long-haul covid symptoms
Receiving a COVID-19 vaccination could offer a dual benefit by not only lowering the likelihood of developing long-haul COVID but also mitigating symptoms for individuals already dealing with this condition.
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Researchers discover covid-19 induces mitochondrial dysfunction
Since the onset of the COVID-19 pandemic caused by the SARS-CoV-2 virus, scientists have been striving to comprehend the underlying reasons for the virus's distinctive and detrimental long-term impacts, distinct from most other coronaviruses.
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Advancing vaccine design: potential of peptide mimicry
A new discovery presents a bioinformatic approach for improving vaccine effectiveness against infectious agents such as COVID-19.
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Are female mice better protected against obesity?
The University of California underwent a mouse study disclosing underlying sex differences in mice for obesity.