news
Opaganib shows promise in preventing ARDS-induced thrombosis
Opaganib reduced blood clot length and weight in a pre-clinical model of Acute Respiratory Distress Syndrome (ARDS).
List view / Grid view
Covid-19
article
RNA sequencing provides insights into why every SARS-CoV-2 infection is different
Associate Professor Pandurangan Vijayanand from La Jolla Institute for Immunology discusses his study into the body’s immune response to SARS-CoV-2 and why this can vary.
news
Biomarkers for predicting COVID-19 disease severity
Scientists have created a prognostic classification model which uses biomarkers to help predict an individual’s risk of developing severe COVID-19 symptoms.
news
New SARS-CoV-2 strain identified in South East England
UK Health Secretary Matt Hancock has said there is a mutated form of SARS-CoV-2 that may be causing a rise in infections in South East England.
news
Genome-wide association study reveals targets for COVID-19 treatments
The study found five key genetic differences when they compared sequences from severe COVID-19 patients to healthy individuals.
article
The Editors’ views: Drug Target Review’s 2020 round-up
The Junior Editors of Drug Target Review, Victoria Rees and Hannah Balfour, discuss some of the most noteworthy news and announcements from this year.
news
Inhaled vaccine induces strong immune response in animal models
Scientists report their phage-based inhaled vaccine delivery system elicited a robust antibody response in both mice and non-human primates.
news
Novel target could treat both SARS-CoV-2 and other coronaviruses
Scientists shows targeting cholesterol or phosphatidylinositol phosphate (PIP) could be a promising strategy to combat multiple coronaviruses.
news
Biomarker for blood vessel damage found in children with SARS-CoV-2
Elevated levels of a biomarker related to blood vessel damage have been found in all children with SARS-CoV-2 infection.
news
Triggering an IgA response could increase COVID-19 vaccine efficacy
Two new studies suggest that SARS-CoV-2-specific IgA antibodies are more neutralising and therefore COVID-19 vaccines should encourage an IgA response.
news
Novel target for pulmonary fibrosis identified using tissue from COVID-19 patients
Study suggests reducing the expression of the methyl-CpG-binding domain 2 (MBD2) protein on macrophages could be a viable therapeutic strategy for lung fibrosis.
news
Oral drug blocks SARS-CoV-2 transmission in ferrets, researchers find
A team has found that their drug Molnupiravir (MK-4482/EIDD-2801) acts as an antiviral against SARS-CoV-2 in pre-clinical studies.
news
Microscopy reveals four classes of SARS-CoV-2 neutralising antibodies
Researchers show that neutralising antibodies targeting the SARS-CoV-2 Spike protein have four distinct structures.
news
Researchers provide new insights into SARS-CoV-2 lung pathology
The new study shows how SARS-CoV-2 significantly remodels cellular processes in just an hour and identifies potential drug targets and therapeutics for COVID-19.
news
Novel peptide therapy improves COVID-19 survival by LEAPS and bounds in mice
Researchers report that their LEAPS COV-19 peptides significantly improved survival in a murine model of COVID-19.
