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Gut bacteria linked to age-related conditions
Study suggests that chronic inflammation in the elderly -- thought to be involved in many age-related diseases -- is due to imbalances in gut bacteria...
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Dementia
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Two new genes linked to Alzheimer’s risk
Researchers have identified two genes that influence a person’s risk of developing Alzheimer’s disease.
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MESO-BRAIN initiative receives €3.3 million in funding
9 June 2016 | By Victoria White, Digital Content Producer
The Meso-Brain project could revolutionise the understanding of disease and lead to new treatments for those with dementia or brain injuries...
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New set of genes associated with stroke identified
8 April 2016 | By Victoria White, Digital Content Producer
Researchers identified a new gene called FOXF2 which increased the risk of having a stroke due to small vessel disease in the brain...
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AbbVie announced as the latest Dementia Consortium partner
16 February 2016 | By Victoria White
AbbVie has been announced as the latest Dementia Consortium partner, joining MRC Technology, Alzheimer’s Research UK, Astex, Eisai and Lilly...
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Neurodegenerative diseases: The potential of cyclophilin inhibition
21 January 2016 | By Hans Fliri PhD, Chairman, Cypralis
Here, Dr Hans Fliri, Chairman and CEO of Selcia and Chairman of Cypralis, presents a strong case for targeting mitochondrial cyclophilin D to prevent progression of chronic neurodegenerative diseases...
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First clinical trial for vaccine targeting Alzheimer’s in people with Down’s syndrome
7 January 2016 | By Nicholas Jackson
Plans for the world’s first clinical trial for a vaccine targeting Alzheimer’s disease-like characteristics in those with Down's syndrome have been announced...
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Memory drug BPN14770 moves into Phase 1 safety trial
4 January 2016 | By Victoria White
BPN14770 may be a possible treatment for dementia and Alzheimer’s disease with less potential for side effects than rolipram...
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Enhancing proteasome activity may prevent dementia
22 December 2015 | By Victoria White
A study suggests that enhancing proteasome activity with drugs during the early stages of Alzheimer’s may prevent dementia and reduce damage to the brain...
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Scientists use light to treat Alzheimer’s disease
16 November 2015 | By Victoria White
Scientists have conducted research to suppress an abnormal assembly of beta-amyloids by using photo-excited porphyrins...
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Experimental Alzheimer’s drug J147 shows anti-aging effects
13 November 2015 | By Victoria White
Mice treated with J147 had better memory and cognition, healthier blood vessels in the brain and other improved physiological features...
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RNA-binding proteins play important role in motor neurone disease
30 October 2015 | By Victoria White
The discovery about the FUS protein could be a major milestone on the path to a treatment for both motor neurone disease and dementia...
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Launch of Dementia Discovery Fund to deliver new dementia treatments by 2025
21 October 2015 | By Kate Douetil
This innovative new global investment fund has gained support from a wide variety of investors, including the UK Government’s Department of Health (DoH), Alzheimer’s Research UK and world-leading major pharmaceutical companies Biogen, GlaxoSmithKline, Johnson & Johnson, Lilly, Pfizer and Takeda...
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UCL and Takeda to identify targets for neurodegenerative diseases
14 October 2015 | By Victoria White
The three-year collaboration will focus on mechanistic approaches for the identification of genes or signalling pathways that modify neurodegenerative disease processes affecting neuronal health...
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Astex Pharmaceuticals joins The Dementia Consortium
12 October 2015 | By Victoria White
The Dementia Consortium is a £3.5m drug discovery collaboration between Alzheimer’s Research UK, MRC Technology, Eisai, Lilly and now Astex...