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Potential target for reducing obesity-related inflammation
16 November 2015 | By Victoria White
Investigators found that a protein called SIRT3 provides resistance to obesity-related inflammatory response...
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Scientists help launch human dark proteome initiative
10 November 2015 | By Victoria White
The initiative aims to accelerate research into biology's "invisible mass" to provide novel insights into cell function and a new frontier in drug discovery...
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Cholesterol-lowering vaccine shows promise in preclinical studies
10 November 2015 | By Victoria White
Scientists from the University of New Mexico and NIH have created a cholesterol-lowering vaccine that leads to reductions in LDL cholesterol in mice and macaques...
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Researchers find way to trigger red blood cells on demand
4 November 2015 | By Victoria White
The discovery could represent a significant step forward in the battle against anaemia...
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Novo Nordisk and UW to explore the role of the brain in obesity
3 November 2015 | By Victoria White
The collaboration aims to understand factors mediating brain control of blood glucose and appetite with the ultimate goal of developing new therapeutic agents for the treatment of diabetes and obesity...
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Medlab to start human trials using its NanoCelle platform
22 October 2015 | By Victoria White
Medlab will apply its nanotechnology delivery system to an existing statin compound, atorvastatin, for patients suffering high levels of cholesterol...
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Lilly announces New York R&D site expansion
12 October 2015 | By Victoria White
Lilly has announced plans to add 30,000 square feet to its research and development site at the Alexandria Centre for Life Science in New York...
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C4XD provides a research update on its IL-17 targeting leads
7 October 2015 | By Victoria White
C4XD’s most advanced compound, an oral Orexin-1 antagonist for the treatment of addiction, is in formal preclinical safety and toxicity studies...
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Scientists develop drug to prevent diabetic enteropathy
2 October 2015 | By Victoria White
Scientists have discovered a protein that 'soaks up' the overproduced hormone that leads to diabetic enteropathy...
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New company LA Cell to focus on cell-penetrating antibody therapies
29 September 2015 | By Victoria White
LA Cell has exclusively licensed technology that enables modified monoclonal antibodies to penetrate into cells and target "undruggable" disease-causing molecules...
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C4XD provides update on diabetes & inflammation compounds
23 September 2015 | By Victoria White
C4XD expects to progress its type 2 diabetes and inflammation programmes into in vivo proof-of-principle testing in the next few months...
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Ion channels: Small molecules versus biologics – the quest for the ideal Nav1.7 inhibitor
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…
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Researchers win EBF funding to advance Wolfram syndrome project
8 September 2015 | By Victoria White
A University of Birmingham research team, developing a treatment for Wolfram Syndrome, has secured £17,000 from the Enterprising Birmingham Fund...
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AMRA and Pfizer team up for MR imaging project
8 September 2015 | By Victoria White
AMRA will collaborate with Pfizer to help provide a better understanding of the relationship between body composition and risk for obesity related diseases...
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New high-throughput screening method could speed drug discovery
19 August 2015 | By Victoria White
Scientists have developed a potentially better and more accurate high-throughput screening technique and have used it to identify 24 drug candidates...
