article
21 September 2015 | By Martin Perkins (National Research Council of Canada), Marzia Martina (National Research Council of Canada)
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…