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Mirror-image peptides of existing drugs provide longer-lasting therapeutic effects
Researchers have developed a new technology for creating more durable disease-fighting molecules which could lead to drugs with longer-lasting effects...
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Diabetes
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EXD2 enzyme identified as key player in mitochondrial protein synthesis
A team of researchers led by IRB Barcelona in Spain have identified a key function of the enzyme EXD2 as being the maintenance of protein production in the mitochondria.
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MAFA gene provides insight into the genomics of diabetes
Scientists have uncovered insights into the genomics of diabetes through the rare case of a family where one gene is associated with two opposing conditions...
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3-D imaging of fat reveals potential targets for new obesity treatments
A new report reveals the inner workings of fat tissue in mice and identifies potential targets for new drugs to treat and prevent obesity and diabetes...
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SBP scientists uncover mechanism for blood vessel regeneration
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.
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Pre-diabetes discovery marks step towards precision medicine
Researchers have identified three specific molecules that accurately indicate insulin resistance - a major predictor of diabetes...
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Stem cells pave the way for new treatment of diabetes
A new study has shown how human stem cells can produce insulin-producing cells that in the future can be transplanted into diabetes patients...
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MAIT cells serve as biomarkers for diabetes
Scientists have discovered that the onset of type 1 diabetes is preceded by modification of MAIT lymphocytes...
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National Physical Laboratory re-launched to improve access to health innovations
NPL's new approach informed by government priorities, consultancy with industry and the NHS, and a century of expertise, will see it focus on some of the world’s biggest health challenges, from supporting the diagnosis and treatment of cancer and dementia, to reducing attrition rates in drug development, to creating new…
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Exosomes identified as the missing link to insulin resistance
Researchers have identified exosomes as the missing link in diabetes...
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A genetic approach to high insulin levels
A team of researchers have succeeded in precisely describing the effects of a frequent genetic mutation in cases of congenital hyperinsulinism...
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New technology could predict the risk of type 2 diabetes
Researchers have announced a new technology-based approach that could lead to a more accurate identification of type 2 diabetes...
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Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
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New marker could refine the process of producing hPSC-derived insulin cells
Scientists at the University of Copenhagen have identified a unique cell surface protein present on human pancreatic precursor cells providing for the first time a molecular handle to purify the cells whose fate is to become cells of the pancreas - including insulin producing cells.
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New research highlights key differences between mice and men
Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.