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Research enables screening millions of human antibodies for new drug discovery
Researchers have outlined a pioneering method of screening a person’s diverse set of antibodies for rapid therapeutic discovery.
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Ebola
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TSRI scientists discover workings of first promising Marburg virus treatment
Scientists at The Scripps Research Institute (TSRI) have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus.
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TSRI study shows how Ebola adapted to better target human cells
3 November 2016 | By Niamh Louise Marriott, Digital Content Producer
A new study csuggests that Ebola virus gained a genetic mutation during the 2013 – 16 epidemic that appears to have helped it better target human cells...
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RedHill teams up with NIAID to evaluate potential Ebola treatment
13 July 2016 | By Victoria White, Digital Content Producer
The collaboration follows encourage results from preliminary non-clinical studies of RedHill’s experimental therapy for the treatment of Ebola...
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Programmable RNA vaccines effective against Ebola and influenza
4 July 2016 | By Victoria White, Digital Content Producer
MIT engineers have developed easily customisable RNA vaccines that can be manufactured in one week and have shown efficacy against ebola and H1N1 influenza...
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Assessing the symptoms of post-Ebola syndrome to improve treatment
12 April 2016 | By Victoria White, Digital Content Producer
A study has assessed the effects of post-Ebola syndrome, that include vision complications, joint and muscle pain, and neurological problems, to improve treatments...
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Single antibody protects non-human primates from Ebola virus
26 February 2016 | By Victoria White
A single monoclonal antibody isolated from a human survivor of Ebola virus completely protected monkeys from lethal infection with the virus...
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Herpesvirus CMV-based vaccine shown to be effective against Ebola
15 February 2016 | By Victoria White
In addition to establishing the potential for CMV-based vaccines against Ebola virus, these results are exciting from the potential insight they give into the mechanism of protection...
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Researchers isolate antibodies that neutralise multiple species of Ebola
22 January 2016 | By Victoria White
Researchers used a high-efficiency method they developed to quickly isolate and generate large quantities of monoclonal human antibodies from the blood of survivors of a 2007 outbreak in Uganda who were infected by the Bundibugyo Ebola virus...
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Antibodies zap both EBOV and SUDV Ebola strains
13 January 2016 | By Victoria White
Researchers have engineered the first antibodies that can potently neutralise the two deadliest strains of the virus that causes Ebola haemorrhagic fever...
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IMI launches Calls to advance drug development in Ebola, Alzheimer’s and AMD
22 December 2015 | By Victoria White
The IMI has launched two Calls for proposals that will advance drug development in Ebola, childhood cancers, neurological disorders, and eye disease...
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Janssen and Bavarian Nordic team up for HPV infection vaccine
21 December 2015 | By Victoria White
Their goal is to develop a therapeutic vaccine which aims to intercept HPV infection-related disease, particularly in those who are diagnosed with HPV early, by enhancing the ability of the immune system to treat chronic infections and prevent progression to cancer...
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Protein Expression: The growing potential of plant-made monoclonal antibodies
The success story of Mapp Pharmaceuticals’ experimental drug, ZMapp, during last year’s Ebola outbreak highlights the potential of plant-made monoclonal antibodies (mAbs) as life-saving treatments.
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TSRI scientists reveal potential treatment for dangerous viral infections
23 November 2015 | By Victoria White
Scientists have shown how a previously unknown process works to promote infection in a number of dangerous viruses, including dengue, West Nile and Ebola...
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Gamma interferon protects mice from Ebola
19 November 2015 | By Victoria White
A new study suggests that gamma interferon, which is an FDA-approved drug, may have potential as an antiviral therapy to prevent Ebola infection when given either before or after exposure to the virus...
