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Brain changes responsible for the appetite effects of cannabis identified
New research on how cannabis use alters eating behaviour could lead to treatments for appetite loss in chronic illness...
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Heart disease
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3D map of CVD genetic interactions could aid future treatments
A 3D map of genetic interactions in CVD could aid researchers investigating future treatments for heat attacks, heart failure and heart rhythm disorders.
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CRISPR technology may improve accuracy of predicting heart disease risk
Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies...
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New target for treating heart failure identified by Penn Medicine researchers
Reversing modifications in diseased heart muscle cell struts called microtubules (MT) can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure.
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Controlling immune cell migration as therapy for heart disease
Researchers in the United States find that the location of the body’s immune cells correlates precisely with their function related to heart disease.
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Early stimulation improves performance of bioengineered human heart cells
Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle...
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Scientists discover promising off-switch for inflammation
Scientists have discovered that itaconate - a molecule derived from glucose - acts as a powerful off-switch for macrophages...
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A1C proteins associated with diabetic complications and heart disease
Protein pathways that are closely linked to changes in both triglyceride and haemoglobin A1c levels in diabetic patients have been identified...
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Researchers create enhanced nanoscaffold for regenerative heart medicine
Biophysicists in Russia have gained greater understanding about the structure of nanofibrous scaffolds – termed nanoscaffolds – in a study that is researching heart tissue regeneration.
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STEEL gene senses inadequate blood flow in microscopic blood vessels
A new study has found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues...
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Study uncovers molecular events that reveal pathway toward heart disease therapy
Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.
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Organ-on-a-chip device successfully models heart disease
A new device that models atherosclerosis can help researchers better understand the disease, develop therapies and diagnose blood health...
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Gene therapy may lower risk for heart disease
Researchers have tested whether a single injection of the gene, LeXis could slow down the development of heart disease...
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Blood marker can predict heart disease risk in type-2 diabetes patients
Measuring a blood marker, copeptin, can successfully predict the risk of heart attacks in people with type-2 diabetes.
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Stem cell patch shows early promise in treating heart failure
In a Phase I clinical trial, heart failure patients treated with patches made from their muscle cells showed improved exercise capacity and heart function after one year. Stem cell patch-based therapy may be a viable heart failure therapy and should be validated in larger clinical trials, researchers conclude.