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Potential target for reducing obesity-related inflammation
16 November 2015 | By Victoria White
Investigators found that a protein called SIRT3 provides resistance to obesity-related inflammatory response...
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Scientists help launch human dark proteome initiative
10 November 2015 | By Victoria White
The initiative aims to accelerate research into biology's "invisible mass" to provide novel insights into cell function and a new frontier in drug discovery...
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Cholesterol-lowering vaccine shows promise in preclinical studies
10 November 2015 | By Victoria White
Scientists from the University of New Mexico and NIH have created a cholesterol-lowering vaccine that leads to reductions in LDL cholesterol in mice and macaques...
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Domainex and ICL team up to discover myocardial infarction therapies
20 October 2015 | By Victoria White
Domainex has been selected as Imperial’s strategic drug discovery partner to provide services including biochemical and biophysical assay development...
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USP19 inhibition protects against muscle wasting
15 September 2015 | By Victoria White
Researchers have discovered a new gene, USP19, involved in the muscle wasting syndrome cachexia that could be a good target for drug development...
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AMRA and Pfizer team up for MR imaging project
8 September 2015 | By Victoria White
AMRA will collaborate with Pfizer to help provide a better understanding of the relationship between body composition and risk for obesity related diseases...
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Human RSV study launched to aid vaccine development
26 August 2015 | By Victoria White
A new study will expose healthy adult volunteers to respiratory syncytial virus (RSV), a virus that causes cold-like symptoms in adults...
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New high-throughput screening method could speed drug discovery
19 August 2015 | By Victoria White
Scientists have developed a potentially better and more accurate high-throughput screening technique and have used it to identify 24 drug candidates...
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Research suggests ion channel blocking drugs could be used in cancer therapy
12 August 2015 | By Author: Katie Sadler, Digital Content Producer, Drug Target Review
Research carried out by University of California San Francisco (UCSF) has revealed ion channel blocking drugs could play a part in cancer therapy. The common class of channel blocking drugs, which are used to treat cardiac, neurological, and psychiatric disorders, could prove to be beneficial in cancer treatment according to…
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Research identifies trigger responsible for regenerating hair and skin after trauma
11 August 2015 | By Katie Sadler, Digital Content Producer, Drug Target Review
Johns Hopkins researchers have identified a novel cell signalling pathway in mice through which mammals can regenerate hair and skin while healing from wounds. The discovery, summarised in an article published on 6th August in the journal Cell Stem Cell, could, they say, eventually help spur the growth of new…
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Novel treatments emerging for human mitochondrial diseases
20 July 2015 | By
Using existing drugs to restore basic biological processes in human cells, researchers may have devised effective treatments for mitochondrial diseases...
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The Francis Crick Institute and GSK join forces to forge new scientific discoveries
14 July 2015 | By Victoria White
The Francis Crick Institute and GSK are to partner up to explore new avenues of medical research and drug discovery across a broad range of diseases...
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Summit Therapeutics publishes preclinical data on disease-modifying potential of utrophin modulation in DMD
13 July 2015 | By Victoria White
Summit Therapeutics has announced the publication of preclinical data on the disease-modifying potential of utrophin modulation in the treatment of DMD...
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Researchers identify two biomarkers linked to severe atherosclerosis
7 July 2015 | By Victoria White
Researchers have created a first-of-its-kind animal model to pinpoint two biomarkers that are elevated in the most severe form atherosclerosis...
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Rambo protein could protect against heart failure
6 July 2015 | By Victoria White
A protein dubbed 'Bcl-Rambo' can protect against heart failure, suggests new research from King's College London and funded by the British Heart Foundation...
