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New agreement to progress cardiovascular disease research
The agreement between Cartherics, The University of Sydney and The University of Queensland will further stem cell-derived heart muscle therapy for heart failure.
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New AI process for accurate enrolment of patients to clinical trial
The AI model screened the medical records of heart failure patients more accurately, quickly and cheaply, compared to study staff.
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Light-activated graphene tattoo shows promise in treating heart rhythm disorders
This article outlines the development of the first cardiac implant made from graphene, which is thinner than a single strand of hair yet still functions like a classical pacemaker. It melds softly to the heart to simultaneously sense and treat irregular heartbeats, making it ideal for conforming to soft, dynamic…
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New drug provides optimism for individuals suffering from heart failure
A newly developed drug displays potential in treating both heart failure and the related sleep apnea.
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Different cardiac reactions to stress hormone in mouse study
US researchers use new imaging technique to see cardiac reactions to noradrenaline, the ‘fight or flight’ hormone.
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Enhanced reprogrammed heart fibroblasts delivered into heart muscle cells
UAB researchers have found that adding TBX20 to the reprogramming cocktail MGT 133 promoted cardiac reprograming.
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Novel gene therapy for heart failure moves closer to clinic
New research by US institutions in pigs shows that knocking down a particular signalling pathway after heart failure renews heart tissue.
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Drug target and candidate for paediatric heart failure identified
A group of researchers has found a drug candidate named TRV027 that can increase the cardiac contractility of neonatal mice.
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Macrophages could be the target of novel heart attack therapies
Research determined macrophages’ role in forming a permanent cardiac scar after a heart attack, the researchers suggest altering this behaviour may make the scar temporary and allow restoration of heart function.
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Kinase identified as potential target for heart failure treatment
A new study has shown that restoring the amount of the kinase, HIPK2, in a kinase-depleted mouse model rescued it from heart failure and identifies HIPK2 as a novel regulator of heart failure progression.
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Human stem cell combination could help damaged hearts live longer
A combination of heart cells derived from human stem cells could lead to developing a treatment for heart failure.
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Hidden culprit in heart failure discovered
A study has identified that PI3K alpha could be the culprit of heart failure, as it binds to gelsolin, suppressing it and preventing it from working...
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Biomarker discovered for heart failure with preserved ejection fraction
A biomarker has been discovered for the most common type of heart failure - heart failure with preserved ejection fraction...
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Protein sequencing method could transform biological research
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
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3D map of CVD genetic interactions could aid future treatments
A 3D map of genetic interactions in CVD could aid researchers investigating future treatments for heat attacks, heart failure and heart rhythm disorders.