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Fighting HIV using anti-cancer immunotherapy
Researchers have used immunotherapy treatments, ordinarily used to treat cancer, to reveal the virus in the cells of people living with HIV...
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Neutralising antibodies could lead to HIV vaccine
Developing an HIV vaccine focuses on discovering the factors responsible for the production of antibodies that neutralise almost all known virus strains...
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IgG3 antibody can block B cells from fighting pathogens during HIV infection
Scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens...
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Computer simulations predict the spread of HIV
Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...
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HIV vaccine elicits antibodies in animals that neutralise dozens of HIV strains
NIH study results represent a major advance for structure-based HIV vaccine design...
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CRISPR used to destroy the regulatory genes of HIV
By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, researchers have succeeded in blocking the production of HIV-1 by infected cells...
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Scientists uncover how HIV evades elimination by the immune system
A team of scientists from Trinity College Dublin has identified the mechanism that enables HIV to evade the immune system, paving the way for a new curative treatment.
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SAMHD1 enzyme may block HIV disease progression
One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works...
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Combination therapy suppresses HIV-like virus in primates
Broadly neutralising antibody treatment may target viral reservoir in monkeys...
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GAPSA reveals new HIV targets
Researchers have developed the first-ever high-throughput, genome-scale imaging-based approach to investigate protein stability...
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Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
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Genomic tools reveal diverse behaviour in immune cells
New research from La Jolla Institute for Allergy and Immunology using single-cell transcriptome analysis yields greater understanding of the human immune system.
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HIV-1 genetic diversity is higher in vaginal tract than in blood during early infection
New evidence supports the existence of genetic 'sieve' on the path from vaginal tract to bloodstream...
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Research enables screening millions of human antibodies for new drug discovery
Researchers have outlined a pioneering method of screening a person’s diverse set of antibodies for rapid therapeutic discovery.
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Promising preclinical drug candidate suppresses HIV
A team of researchers have tested a chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose...