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Combatting HIV using gene therapy
Researchers have created a nanomedicine loaded with siRNAs, which demonstrated a 73 percent reduction in HIV replication.
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HPV
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HPV-associated head and neck cancers identified
Human papillomavirus (HPV)-associated head and neck cancers, specifically head and neck squamous cell carcinoma (HNSCC), are on the rise worldwide. Yet, the factors contributing to these tumours and their varying responses to treatment remain poorly understood.
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HPV vaccine cost reimbursement could hinder vaccine access
Bare minimum reimbursement rates could be why some clinics may be struggling to offer HPV vaccination in the US.
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Study highlights possibility of using 3D organoids of the cervix to test drugs
A new study modelled chlamydia and HPV co-infection in patient-derived ectocervix organoids to reveal distinct cellular reprogramming.
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Scientists establish genetic link between HLA and genital warts
The discovery of a link between the human leukocyte antigen (HLA) and genital warts may lead to mRNA-based vaccines against HPV and other diseases.
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“Ultrasensitive” HPV detection paves way for precision treatment
A new study sequenced tumour DNA for the “ultrasensitive” detection of HPV, further honing precision treatment of the illness.
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First patient-derived organoid model for cervical cancer developed
Novel organoid models of cervical cancer and a healthy human cervix have been developed to study the condition and its progression.
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CD47 blockade could work as immunotherapy across multiple diseases
Researchers have demonstrated that blocking CD47-mediated signalling in mice can enhance the speed of pathogen clearance, presenting a new potential form of immunotherapy.
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Why invest in creating a modifiable drug framework?
Drug Target Review spoke with CUE Biopharma’s President and CSO to find out how and why they created the ImmunoSTAT platform and the ways it may benefit drug design in the future.
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E6/Myc binding provides potential treatment strategy for HPV
A study that teases apart the biological mechanisms by which HPV cause cancer, has found a strategy that may provide targeted treatment...
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Artes and BioSun to co-develop on HPV vaccine
4 November 2016 | By Niamh Louise Marriott, Digital Content Producer
The agreed long-term collaboration will take strengths from both companies to collaborate on the HPV vaccine although financial details of this agreement...
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Hookipa receives €4.16 million cancer grant from FFG
18 October 2016 | By Niamh Louise Marriott, Digital Content Producer
The grant for the second year of a multi-year R+D project and will be used for Hookipa’s arenaviral vector technologies, cancer immunotherapies and to...