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Huntington's disease

news

CRISPR technique skips over portions of genes that can cause disease

17 August 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...

UBR5

UBR5

news

UBR5 protein may reduce neurodegeneration in Huntington’s disease

27 July 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease...

Huntington's

Huntington's

news

New insight into Huntington’s disease may open door to drug development

10 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition...

Huntington's

Huntington's

news

Molecular alterations provide insight into Huntington’s disease

21 June 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have applied their high-throughput, multi-pronged approach to Huntington's disease, and uncovered the functional significance of various molecular changes...

Huntington's

Huntington's

news

A link between Huntington’s disease and rheumatoid arthritis identified

15 May 2018 | By Dr Zara Kassam (Drug Target Review)

Epigenomic analyses may lead to other unexpected findings and novel therapeutic drug targets for many diseases

news

Lab-on-a-chip device mimics eye damage due to intense light

11 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers create eye neuron network model to study retinal diseases, possible treatment options...

CRISPR

CRISPR

news

CRISPR used to edit DNA outside of the cell

23 April 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed a breakthrough CRISPR gene-editing tool, that could allow researchers to quickly and precisely engineer multiple changes to the genetic code...

neurological

neurological

news

New method allows scientists to watch brain cells interacting in real time

6 April 2018 | By Drug Target Review

Findings could deepen understanding of neurological disorders...

Huntington's

Huntington's

news

Animal model of Huntington’s offers advantages for testing treatments

2 April 2018 | By Dr Zara Kassam (Drug Target Review)

Using genetic engineering technology, a team of scientists have established an animal model of Huntington's disease...

CRISPR/Cas9

CRISPR/Cas9

news

CRISPR/Cas9 variant holds promise for Huntington’s disease treatment

26 February 2018 | By Dr Zara Kassam (Drug Target Review)

Improvements to gene-editing techniques hold promise for inactivating the defective gene responsible for this as-yet incurable disease...

Huntington's disease

Huntington's disease

news

Huntington’s disease provides new cancer weapon

13 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...

Huntington's

Huntington's

news

Reprogrammed brain cells exhibit symptoms of Huntington’s disease

6 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder...

Huntington's

Huntington's

news

Uncovering the early origins of Huntington’s disease using CRISPR engineered embryonic stem cells

29 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a system to model Huntington's in human embryonic stem cells...

Huntington’s disease

Huntington’s disease

news

IONIS-HTTRx lowers deadly Huntington’s disease protein

12 December 2017 | By Dr Zara Kassam (Drug Target Review)

The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial…

huntington's disease

huntington's disease

news

New data network for Huntington’s disease research

17 July 2017 | By Niamh Marriott (Drug Target Review)

The first data network for this research could also be the blueprint for similar data networks for research into other conditions...

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