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Kidney Cancer

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Researchers have linked resistance to kidney cancer treatment to low mitochondrial content in cancer cells

28 June 2022 | By Ria Kakkad (Drug Target Review)

When the researchers increased the mitochondrial content with an inhibitor, the cancer cells responded to the treatment.

news

Researchers investigate gene network to identify “cancer driver genes”

14 December 2021 | By Anna Begley (Drug Target Review)

The new study looked at the network of gene-gene interactions associated with cancer onset and progression to identify therapeutic targets.

news

Therapeutic target for aggressive cancers discovered through CRISPR

5 August 2021 | By Anna Begley (Drug Target Review)

The RNA-modifying protein METTL1 could be targeted to treat some types of aggressive cancers, including brain, blood and kidney.

Red blobs (indicating T cells) surrounding and touching larger white blobs (acting as cancer cells) - idea of T cell therapy for cancer

news

New ‘smart’ cell therapies show promise in solid tumours

27 November 2020 | By Hannah Balfour (Drug Target Review)

By combining machine learning and T-cell engineering researchers were able to develop cell therapies that can selectively and effectively target and destroy solid tumours.

news

Activating c-Cbl gene causes immune system to attack cancer cells

3 January 2020 | By Hannah Balfour (Drug Target Review)

Upregulation of the c-Cbl gene causes degradation of the immune checkpoint protein PD-1 and may provide a possible new avenue for cancer therapies, according to researchers.

news

NOX4 mechanism identified as a culprit in kidney cancer evolution

25 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the molecular mechanism that causes kidney cancer to resist drug treatment...

news

Improved analysis of kidney cancer

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

A research team have discovered that in the Cancer Genome Atlas database the gene expression in reference samples differs from normal tissue, depending on where in the kidney the samples happen to have been taken from...

news

New mouse model to better kidney cancer treatment

31 May 2017 | By Niamh Marriott (Drug Target Review)

Research in the field of kidney cancer, also called renal cancer, is vital, because many patients with this disease still cannot be cured today.

news

Obesity behind surge in kidney cancers

24 April 2017 | By Niamh Marriott (Drug Target Review)

Kidney cancer rates have increased by 40% over the last 10 years in the UK, and the rise is expected to continue. An estimated 20,000 kidney cancer cases have been caused by obesity over the last decade in England, according to new figures from Cancer Research UK.

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Kidney Cancer