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Synthetic antibody treats congenital myasthenia in mice
Researchers have designed an antibody that attaches to MuSK, which prevented early lethality of mice with congenital myasthenia.
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Lou Gehrig's Disease
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Researchers map pathoconnectome of eye disease and retinal circuitry
Scientists have produced the first pathoconnectome - an open access map for other researchers that shows how eye disease can alter retinal circuitry.
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Sensory neurons can be used to discover therapies for ALS
New approach for testing for ALS may be useful to reverse debilitating disease...
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Drugs in development for cancer may also fight brain diseases
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
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Changes to specific MicroRNA involved in development of Lou Gehrig’s disease
A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS).
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Antibodies protect nerve-muscle connections in Lou Gehrig’s disease
A study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive ALS...
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Super-silenced DNA study hints at new ways to reprogram cells
Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity.
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Protein associated with ALS points to possible targets for therapeutic intervention
Scientists may have found possible targets for therapeutic interventions in the fight against Lou Gehrig’s disease.
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New gene variant identified in ALS provides treatment hope
A new study shows that a variant in UBQLN4 gene has been associated with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS). The study also describes how this gene variant disrupts a cellular process that drives motor neuron development. This new insight opens the door to potential treatment targets for…