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WDR74 protein identified as lung cancer and melanoma therapeutic target
Researchers have revealed that the WDR74 protein plays a key role in lung cancer and melanoma, including metastasis, indicating it may be a potential drug target.
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Genes associated with heavy alcohol use may also impact compulsive behaviour and addiction
A study suggests there may be common genetic pathways between alcohol use disorder and other addictions, so GWAS identification of affected genes could provide the targets for new therapies.
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Cancer cells killed in mice using copper-based nanomaterials
Copper oxide nanoparticles have successfully killed tumour cells in mice and when combined with immunotherapy, could work as a vaccine for cancer.
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Blocking kinase could provide treatment for prostate cancer
Researchers have found that inhibiting a kinase in mice leads to the death of prostate cancer cells, providing a potential therapeutic target.
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Study reveals antioxidant role in spread of lung cancer
Researchers have discovered that lung cancer cells metastasise using antioxidants, informing potential future therapies.
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Heme-sequestering peptides may help stall lung cancer
Scientists have demonstrated that the growth rate of the majority of lung cancer cells relates directly to the availability of a crucial oxygen-metabolising molecule.
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Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours
Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
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MicroRNA regulates drug tolerance in subset of lung cancers
Newly identified pathway offers promising targets for preventing tumour relapse...
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Microfluidics device to detect cancer cells in blood
A recently developed microfluidics device is able to detect and separate out cancer cells in blood, without the need for dilution...
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Taking a BiTE out of lung cancer
Bispecific T-cell engager technology (BiTE) could be used to quickly and accurately diagnose patients suffering from lung cancer...
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PD-L1 assay specifically selects ideal patients for cancer treatment
An assay assessing the level of programmed death ligand 1 (PD-L1) could help to determine the method of treatment for lung cancer patients...
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Catching lung cancer early using molecular profiling
Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...
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Starving lung cancer could be an effective treatment
A recently discovered enzyme could lead to the development of a treatment where cancer cells are starved of 'food' provided by this protein...
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Paclitaxel acting as an immune response modulator
Brazilian researchers have discovered that a drug widely used as for chemotherapy also acts as an immune response modulator...
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Investigating tumour microenvironments for more effective treatments
Tumour microenvironments give insights into more effective therapies against lung cancer, a bigger killer than colon, prostrate and breast cancers combined...