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Malaria

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Rhomboid protease role observed using dynamic imaging

28 October 2019 | By Rachael Harper (Drug Target Review)

Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication.

news

Protective antibodies identified that could be key to malaria vaccine

18 June 2019 | By Drug Target Review

A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.

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Study reveals potential for malaria prevention vaccine

6 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have identified a novel drug target for the prevention of malaria.

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Genomic approach to studying widespread malaria

11 February 2019 | By Drug Target Review

Researchers have suggested that the most widespread human malaria parasite could be studied and possibly treated using genomics...

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Scientists image antibodies working together against malaria

24 October 2018 | By Drug Target Review

Cryo-EM was used to image the antibodies attaching to the circumsporozoite protein, which is the most abundant protein on the surface of malaria...

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Nonresponsive NK cells directly impact malaria severity

5 October 2018 | By Drug Target Review

The failure of natural killer cells (NK cells) to respond to infection explains why malaria causes a worse reaction in some patients than others.

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Promising new vaccine developed for vivax malaria

20 September 2018 | By Drug Target Review

A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...

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Six compounds identified from 70,000 to help eradicate malaria

18 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...

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Computational analysis identifies a new clinical phenotype of severe malaria

4 September 2018 | By Drug Target Review

Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...

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Malaria vaccine targets PMIF

13 July 2018 | By Drug Target Review

A new malaria vaccine targets the protein PMIF, which is crucial in the life cycle of malaria parasites...

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CIS43 antibody prevents malaria in mice

20 March 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have discovered a human antibody that protected mice from infection with the deadliest malaria parasite, Plasmodium falciparum...

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CRISPR/Cas9 technique suppresses malaria infection in mosquitos

9 March 2018 | By Dr Zara Kassam (Drug Target Review)

Genome editing could enable new strategies to prevent malaria transmission to humans...

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The spreading mechanism of malaria parasites provides new drug target

22 February 2018 | By Drug Target Review

A team of researchers in the UK have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, thus offering potential new treatment targets.

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Five new malaria targets that could lead to an effective vaccine

23 October 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified five targets that reduce the parasite's ability to invade red blood cells...

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Optibrium, Imperial College and DNDi to collaborate on drug development

30 May 2017 | By Niamh Marriott (Drug Target Review)

The collaboration will provide MSc students with industry-relevant learning tools and pharma with a new pipeline of candidate compounds.

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Malaria