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metabolic disease

news

Discovery of a signalling pathway that activates desire to exercise

21 August 2024 | By Drug Target Review

The study highlights the possible therapeutic significance of targeting the pathway for treating obesity and metabolic disease.

news

Mesothelial cells in omental adipose tissue hinder adipogenesis

13 May 2024 | By Drug Target Review

The discovery that omental fat has a mechanism to limit adipocyte formation may lead to new treatments for obesity and metabolic disease.

news

Delivering a human monoclonal IgG1 antibody to the brain

5 January 2024 | By Drug Target Review

Adding a biodegradable polymer at the hinge and near hinge regions of trastuzumab enabled its movement across the blood-brain barrier.

3d illustration concept of Blood cells and sugar cubes

news

Research provides a potential drug target to treat diabetes and obesity

7 April 2022 | By Ria Kakkad (Drug Target Review)

A new study by University of Texas Health Science Center at San Antonio has found that boosting liver mRNAs in obese mice reduces appetite and body weight.

mouse perched on researcher's gloved hands

news

NLRP3 inflammasome ‘off switch’ reverses effects of chronic inflammation

6 February 2020 | By Hannah Balfour (Drug Target Review)

Research into age-related chronic inflammatory disorders has identified an ‘off switch’ on the NLRP3 inflammasome that could be targeted in new therapies.

news

Brain changes responsible for the appetite effects of cannabis identified

17 July 2018 | By Dr Zara Kassam (Drug Target Review)

New research on how cannabis use alters eating behaviour could lead to treatments for appetite loss in chronic illness...

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Recommended

metabolic disease

Discovery of a signalling pathway that activates desire to exercise

Mesothelial cells in omental adipose tissue hinder adipogenesis

Delivering a human monoclonal IgG1 antibody to the brain

Research provides a potential drug target to treat diabetes and obesity

NLRP3 inflammasome ‘off switch’ reverses effects of chronic inflammation

Brain changes responsible for the appetite effects of cannabis identified