news Brain cells found to transfer material to neurons in mice 21 April 2023 | By Taylor Mixides (Drug Target Review) Researchers have discovered that oligodendrocyte-lineage cells transfer cell material to neurons in a mouse brain. They have provided the first evidence of coordinated nuclear interaction between these cells and neurons.
news Scientists ‘reinvent’ petri dish for growing live brain tissue 22 February 2022 | By Ria Kakkad (Drug Target Review) Researchers have innovated the petri dish to be able to grow and age live brain cells from patients with neurological disorders.
article Refreshing how we approach neuroscience with a novel screening technology 9 April 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review discusses how NETSseq, a novel profiling technology, is bringing new insights to neurodegenerative and psychiatric diseases.
news Novel ligands developed with high affinity for Alzheimer’s receptors 7 April 2020 | By Victoria Rees (Drug Target Review) A group of researchers has synthesised a new class of ligands which bind with high affinity to imidazoline I2 receptors, a drug target for Alzheimer's disease.
news BT13 molecule shows promise for halting Parkinson’s 18 February 2020 | By Nikki Withers (Drug Target Review) A molecule has been shown to increase dopamine levels in the brains of mice, offering hope for stopping the progression of Parkinson’s.
news Researchers discover α-synuclein clue to treating Parkinson’s 17 January 2020 | By Victoria Rees (Drug Target Review) A study has shown that fruit fly larvae lacking a certain region of the α-synuclein protein did not exhibit Parkinson’s symptoms, indicating a potential target.
news Screening platform reveals compounds that protect neuronal mitochondria 13 January 2020 | By Victoria Rees (Drug Target Review) Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
news Exosomes used by researchers as form of novel gene therapy 17 December 2019 | By Victoria Rees (Drug Target Review) A study has demonstrated that exosomes can be used as nanocarriers for therapeutic contents, as a new type of gene therapy.
news Rhomboid protease role observed using dynamic imaging 28 October 2019 | By Rachael Harper (Drug Target Review) Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication.
news Neurodegeneration enzyme identified in mouse models 25 June 2019 | By Drug Target Review A new study has found an enzyme in the brains of mice models which induces Parkinson’s, suggesting future drug target.
news Molecule which targets Parkinson’s protein identified 6 June 2019 | By Victoria Rees (Drug Target Review) A new study has identified a molecule which targets a protein linked with Parkinson’s.
news Compounds in coffee may fight Parkinson’s 11 December 2018 | By Drug Target Review Caffeine plus another compound in coffee beans' waxy coating may protect against brain degeneration...
news Ageing hallmark in neurons discovered by biologists 27 November 2018 | By Drug Target Review Oxidative stress occuring in neurons produces unusual piles of short snippets of RNA and could be a marker of neurodegenerative diseases...
news Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease 14 November 2018 | By Drug Target Review A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
news Better drug delivery through the blood-brain barrier 19 October 2018 | By Iqra Farooq (Drug Target Review) Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue...
