news
Neurodevelopmental defects seen in mini-brains with ANG mutation
Researchers found that ANG in its mutated form slows stem cell differentiation, resulting in neurodevelopmental defects in adult nerve cells.
List view / Grid view
Parkinson's disease (PD)
news
Improved targeted ocular spectroscopy for better diagnosis
In vitro and in vivo experiments highlight the advantages of a new targeted spectroscopy system for many eye diseases.
news
Nano-sized traps enable better study of proteins
Researchers have developed a new method to study protein clumps that occur in many difficult-to-treat diseases.
news
Incorporating microglia into brain organoids
iPS-cell-derived microglia in brain organoids have enabled scientists to understand early brain development and microglia-associated disease.
article
New avenues for rare disease treatment
Drugs that boost autophagy hold great promise in preventing and halting neurodegenerative disorders. By ramping up the cell’s waste disposal system, they stimulate the removal of the toxic proteins that are a hallmark of brain conditions such as Alzheimer’s disease and Parkinson’s disease. Now, scientists are harnessing the power of…
news
New cell discovery shakes up neuroscience
Scientists have identified a novel cell type that combines astrocytic characteristics with the machinery for synaptic transmission. This discovery resolves years of debate in the field.
article
Brain macrophage in Parkinson’s disease neuroinflammation
A growing body of evidence pinpoints neuroinflammation as a pivotal factor driving brain-related pathogenesis. Yet, a crucial question lingers: among the various immune cell groups residing within the brain, which one orchestrates this inflammatory reaction?
article
Therapeutic frontiers: the potential of RRx-001 and AdAPT-001
Meet RRx-001 (nibrozetone) and AdAPT-001—two cutting-edge compounds crafted by EpicentRx. In this Q&A session with Dr Bryan Oronsky, Chief Development Officer at EpicentRx, we discover novel mechanisms, diverse applications, and game-changing impact on cancer treatment and beyond.
news
Three distinct brain circuits in the thalamus contribute to Parkinson’s symptoms
Targeting these brain circuits could offer a new way to reverse motor dysfunction and depression in Parkinson’s disease patients.
article
Are scientists closing in on vaccines for Alzheimer’s and Parkinson’s?
Protecting against conditions that appear in older generations is increasingly becoming a focus of the medical industry. In this article, Dr Andrea Pfeifer, CEO and Director of AC Immune, discusses the current landscape of vaccine development for neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
news
NINDS awards Sinopia $3.3m for development of Parkinson’s drug candidate
Sinopia has been awarded a $3.3 million Fast-Track SBIR grant to fund the study for its small molecule candidate for Parkinson’s disease.
news
Promising pre-clinical data announced for Parkinson’s drug
Stealth BioTherapeutics reported positive data from a pre-clinical study evaluating SBT-272 in a murine model of Parkinson's disease.
news
Quantifying method developed to improve neurodegeneration studies
Researchers have created a new method to quantify protein droplets involved in neurodegenerative diseases, enhancing the study of treatments.
news
Farnesol shows potential to prevent and treat Parkinson’s disease
Researchers have added to evidence that farnesol prevents and reverses brain damage linked to Parkinson’s disease in mouse models.
news
Drug target to halt progression of Parkinson’s disease identified
Scientists have shown that trapped LC3B protein in brain cells enables Parkinson's disease to spread, presenting a drug target.