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Parkinson's disease

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Anle138b blocks toxic ion flow linked to Alzheimer’s disease

5 December 2017 | By Dr Zara Kassam (Drug Target Review)

A new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease by stopping toxic ion flow in the brain...

news

CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

CRISPR engineered to edit single RNA letters

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...

news

Phenogenetic map created for stem cell models of neurological diseases

19 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...

news

Modified CRISPR technique used to combat Parkinson’s disease

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

Biological engineers identify genes that protect against protein linked to Parkinson's disease...

Janusz Kulagowski, Drug Discovery Manager at Parkinson's UK

news

Parkinson’s UK Drug Discovery Manager joins DTR advisory board

28 September 2017 | By Steve Bremer (Drug Target Review)

Drug Target Review welcomes Janusz Kulagowski to its advisory board ...

news

Novel genetic mutation discovered in Parkinson’s disease

14 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the first case of a patient with Parkinson's disease carrying a mutation in the ACMSD gene...

news

New potential strategy to combat Alzheimer’s disease

1 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have revealed the molecular mechanism behind a rare mutation has been associated with numerous neurodegenerative diseases...

news

Antibody targets create potential for a unified treatment approach

29 August 2017 | By Dr Zara Kassam (Drug Target Review)

Antibody targets thought to cause the most damage in neurological disorders, creates potential for a unified treatment approach...

news

Immune system may mount an attack in Parkinson’s disease

28 July 2017 | By Steve Bremer (Drug Target Review)

T cells may play an important role in Parkinson’s disease (PD), according to a new study...

news

Balance and movement improved in animal model of Parkinson’s disease

12 June 2017 | By Niamh Marriott (Drug Target Review)

Researchers have developed a molecular compound that improves balance and coordination in mice with early stage Parkinson's disease.

news

Alzheimer’s, Parkinson’s, and Huntington’s diseases share common crucial feature

24 May 2017 | By Niamh Marriott (Drug Target Review)

A study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a ability to cause damage...

news

Bowel cancer medication could help combat early-onset Parkinson’s disease

16 March 2017 | By Niamh Marriott (Drug Target Review)

People with certain forms of early-onset Parkinson’s disease could potentially benefit from taking a medication used to treat certain forms of cancer.

news

Mitochondrial lipids as potential targets for Parkinson’s disease

14 February 2017 | By Niamh Marriott (Drug Target Review)

Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells’ mitochondria, organelles that produce energy.

news

JPND launches €23 million call for neurodegenerative disease research

16 January 2017 | By Niamh Marriott (Drug Target Review)

Neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease are a global health, economic and social emergency.

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Parkinson's disease