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Parkinson's disease

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The combination of two proteins exerts a regenerating effect in Parkinson’s disease

16 January 2018 | By Drug Target Review

Parkinson’s research has led to the development an experimental model that allows different stages of Parkinson’s disease to be reproduced.

news

Mitochondrial disease can be inherited from healthy parents

15 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have shown for the first time how children can inherit a severe -- potentially fatal - mitochondrial disease from a healthy mother...

Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson's

news

Researchers identify new melatonin-based molecular targets for design of new drugs against Parkinson’s

15 January 2018 | By Drug Target Review

A team of scientists has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.

news

Brainstem changes identified in Parkinson’s disease

5 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death...

news

Healthy mitochondria may prevent Alzheimer’s disease

7 December 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have provided a therapeutic approach to slow down the progression of neurodegeneration in Alzheimer's disease...

news

Anle138b blocks toxic ion flow linked to Alzheimer’s disease

5 December 2017 | By Dr Zara Kassam (Drug Target Review)

A new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease by stopping toxic ion flow in the brain...

news

CXCR7 receptor reveals potential therapeutic target to reduce brain inflammation

6 November 2017 | By Dr Zara Kassam (Drug Target Review)

CXCR7 receptor identified as a potential therapeutic target for controlling multiple sclerosis, Parkinson's and AIDS...

news

CRISPR engineered to edit single RNA letters

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...

news

Phenogenetic map created for stem cell models of neurological diseases

19 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...

news

Modified CRISPR technique used to combat Parkinson’s disease

13 October 2017 | By Dr Zara Kassam (Drug Target Review)

Biological engineers identify genes that protect against protein linked to Parkinson's disease...

Janusz Kulagowski, Drug Discovery Manager at Parkinson's UK

news

Parkinson’s UK Drug Discovery Manager joins DTR advisory board

28 September 2017 | By Steve Bremer (Drug Target Review)

Drug Target Review welcomes Janusz Kulagowski to its advisory board ...

news

Novel genetic mutation discovered in Parkinson’s disease

14 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the first case of a patient with Parkinson's disease carrying a mutation in the ACMSD gene...

news

New potential strategy to combat Alzheimer’s disease

1 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have revealed the molecular mechanism behind a rare mutation has been associated with numerous neurodegenerative diseases...

news

Antibody targets create potential for a unified treatment approach

29 August 2017 | By Dr Zara Kassam (Drug Target Review)

Antibody targets thought to cause the most damage in neurological disorders, creates potential for a unified treatment approach...

news

Immune system may mount an attack in Parkinson’s disease

28 July 2017 | By Steve Bremer (Drug Target Review)

T cells may play an important role in Parkinson’s disease (PD), according to a new study...

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Parkinson's disease