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JPND launches €23 million call for neurodegenerative disease research
Neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease are a global health, economic and social emergency.
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Parkinson's disease
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Breakthrough in production of dopamine neurons for Parkinson’s disease
31 October 2016 | By Niamh Louise Marriott, Digital Content Producer
"In our preclinical assessments of stem cell-derived dopamine neurons we noticed that the outcome in animal models varied dramatically, even though...
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Asceneuron receives Parkinson’s research grant from the Michael J. Fox Foundation
6 October 2016 | By Niamh Louise Marriott, Digital Content Producer
The grant from the MJFF therapeutic pipeline program will support studies for the optimisation of molecules to provide preclinical proof of concept in...
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Study of gene mutations improves understanding of inherited Parkinson’s disease
29 July 2016 | By Mandy Parrett, Editorial Assistant
Scientists have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson’s disease.
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New drug could stop Parkinson’s Disease
20 July 2016 | By Niamh Louise Marriott, Digital Content Producer
Scientists discovered an interaction in neurons that contributes to Parkinson's disease, showing how drugs now under development could block the process...
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Scientists find evidence linking Parkinson’s to autoimmune disease
27 June 2016 | By Victoria White, Digital Content Producer
Scientists have discovered that two genes associated with Parkinson's disease, known as PINK1 and Parkin, are key regulators of the immune system...
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A protective strategy against pesticide-linked Parkinson’s disease
15 June 2016 | By Victoria White, Digital Content Producer
UCLA researchers have found that elimination of the α-synuclein protein protected zebrafish against ziram-induced loss of dopamine neurons...
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Neural stem cell transplants show promise in Parkinson’s disease
8 June 2016 | By Victoria White, Digital Content Producer
A study has shown that grafting hpNSCs into non-human primates modelled with PD promoted behavioural recovery and increased dopamine concentrations...
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TMEM230 gene shown to cause Parkinson’s disease
6 June 2016 | By Victoria White, Digital Content Producer
Scientists from Northwestern University have discovered a new cause of Parkinson's disease - mutations in a gene called TMEM230...
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MJFF supports two stem cell projects to speed new Parkinson’s disease therapies
25 May 2016 | By Victoria White, Digital Content Producer
MJFF is to fund two projects leveraging the promise of engineered stem cells to speed new therapies and deeper understanding of Parkinson's disease...
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HuMiX – the new human microbiome research tool
11 May 2016 | By Victoria White, Digital Content Producer
Scientists have proven that a model of the human gut - HuMiX - is representative of the actual conditions and processes that occur within our intestines...
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Jakinibs prevent neurodegeneration in rat models of Parkinson’s disease
3 May 2016 | By Victoria White, Digital Content Producer
Oral administration of a Jakinib lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's...
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Cell transplant that responds to designer drugs treats Parkinson’s disease
28 April 2016 | By Victoria White, Digital Content Producer
Su-Chun Zhang created two related cell types. When the cells detect the designer drug, one type ramps up production of dopamine; the other chokes it off...
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Mapping neurons to improve Parkinson’s disease therapies
21 April 2016 | By Victoria White, Digital Content Producer
Researchers have mapped out the pathways of a set of neurons responsible for the kinds of motor impairments found in patients with Parkinson's disease...
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Researchers identify when Parkinson’s proteins become toxic
15 March 2016 | By Victoria White
Their work could help unravel how and why people develop Parkinson’s, and aid in the search for potential treatments...
