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rheumatoid arthritis

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Scientists identify key protein fuelling autoimmune attacks

11 February 2025 | By Drug Target Review

Mass General Brigham researchers found granzyme K (GZMK) drives inflammation in autoimmune diseases, opening new possibilities for targeted treatments.

news

Rare types of helper T cells uncovered

12 July 2024 | By Drug Target Review

Researchers have created a new T cell atlas which could aid the development of novel drug therapies for immune-mediated diseases.

news

New study challenges assumptions about the development of RA

7 May 2024 | By Drug Target Review

Scientists have discovered that each rheumatoid arthritis patient possesses a unique and diverse set of ACPAs.

news

Improving treatments for rheumatoid arthritis patients

7 February 2024 | By Drug Target Review

Researchers found that resolvinT4 restores protective macrophage biological activities in rheumatoid arthritis patients.

news

New method to develop therapeutics for autoimmune diseases

30 November 2023 | By Drug Target Review

A technique that can sort millions of CRISPR-edited cells based on their secretion patterns has been developed to treat autoimmune diseases.

news

Potential for improved rheumatoid arthritis treatment

9 November 2023 | By Drug Target Review

Six types of inflammation with various cell types and disease pathways identified may provide better treatment of rheumatoid arthritis.

news

AI tools aid the discovery of super tight-binding antibodies

2 February 2023 | By Izzy Wood (Drug Target Review)

An AI strategy developed by US scientists could accelerate the development of new antibody drugs.

Small crying girl child feel scared of injection in hospital. Nurse or doctor hands with syringe, little kid afraid of vaccination. Healthcare and medicine concept. Flat vector illustration.

news

A promising oral drug delivery platform could replace injections with pills

6 January 2023 | By Ria Kakkad (Drug Target Review)

The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.

news

Machine-learning technique classifies key immune cells for suite of diseases

19 October 2022 | By Izzy Wood (Drug Target Review)

Trinity College Dublin has developed a new technique that accurately determines the state of macrophages.

news

New screening technique to accelerate the discovery of cancer-fighting drugs

22 April 2022 | By Ria Kakkad (Drug Target Review)

The novel screening technique can identify molecules that can disable dangerous proteins before they cause diseases by blocking them from interacting with a cell’s DNA.

Woman with arthritus holding hand highlighted in red

news

Rheumatoid arthritis discovery may lead to novel inflammation blockers

24 November 2021 | By Anna Begley (Drug Target Review)

A new study links tumour necrosis factor seen in rheumatoid arthritis with T cell dysfunction, potentially leading to new therapies.

Woman with rheumatoid arthritis chhecking medicines

news

Experimental vaccine a major breakthrough for rheumatoid arthritis

5 October 2021 | By Anna Begley (Drug Target Review)

A protein-based vaccine has proven a promising option to prevent rheumatoid arthritis, improving bone quality in animal models.

article

Determining the structure of nanobodies using nuclear magnetic resonance spectroscopy

23 September 2021 | By Professor Gennaro Esposito (NYU Abu Dhabi)

Scientists at the New York University (NYU) Abu Dhabi have used nuclear magnetic resonance (NMR) techniques to determine the structure of a specific nanobody, Nb23. Drug Target Review’s Victoria Rees spoke with lead researcher Professor Gennaro Esposito to find out how their findings could lead to a better understanding of…

news

Gut microbiome linked to rheumatoid arthritis prognosis

15 September 2021 | By Anna Begley (Drug Target Review)

New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.

article

Targeting TNF to treat Dupuytren’s disease, frozen shoulder and POCD

20 April 2021 | By Dr James Woody (180 Life Sciences)

Dr James Woody discusses off-patent indications for anti-TNF to address unmet patient needs in pain, inflammation and beyond.

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rheumatoid arthritis