Genetic deletion permanently prevented type 1 diabetes development in mice
Researchers observed that deleting the IRE1-alpha gene caused beta cells to de-differentiate and then re-differentiate in mice, preventing immune system auto-activation.
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Researchers observed that deleting the IRE1-alpha gene caused beta cells to de-differentiate and then re-differentiate in mice, preventing immune system auto-activation.
Dr Nicolas Poirier reveals how immunotherapies can be designed to recalibrate the immune system for long-term maintenance of autoimmune remission.
Researchers have discovered that type 1 diabetes patients have low levels of growth differentiation factor 15 (GDF15) in their pancreatic β cells, unlocking a potential alternative to life-long type 1 diabetes disease management.
A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.
A new study from the University of Eastern Finland has shown that peripheral T helper cells may have a role in the development of type 1 diabetes.
Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...
EBV may trigger some cases of lupus, say NIH-supported researchers...