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Yellow fever

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Spike gene mutants could be used as novel COVID-19 vaccine

27 August 2021 | By Anna Begley (Drug Target Review)

SARS-CoV-2 Spike gene mutants may be developed into immunogens for new vaccines against COVID-19, a study in hamsters has shown.

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Mosquito protein could hold key to therapeutics against flaviviruses

11 March 2021 | By Victoria Rees (Drug Target Review)

A study has shown the mosquito protein AEG12 inhibits flaviviruses, the family of viruses that cause yellow fever, dengue and Zika.

yellow viral particle surrouned by blue antibodies

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2B7 antibody could be the breakthrough needed for dengue fever therapies

8 January 2021 | By Hannah Balfour (Drug Target Review)

Scientists show that an antibody targeting a protein acting as a viral toxin, can prevent the dengue virus from infecting human cells.

orange virus surrounded by hundreds of small blue antibodies on a red background

news

White blood cells as a novel early indicator of vaccine efficacy

21 May 2020 | By Hannah Balfour (Drug Target Review)

Researchers demonstrate that a subpopulation of circulating white blood cells can act as an early indicator of vaccine efficacy, with potential implications for COVID-19 drug development.

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Recommended

Yellow fever

Spike gene mutants could be used as novel COVID-19 vaccine

Mosquito protein could hold key to therapeutics against flaviviruses

2B7 antibody could be the breakthrough needed for dengue fever therapies

White blood cells as a novel early indicator of vaccine efficacy