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Zika virus

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Experimental drug reduces zika virus replication and protects developing mouse pups

21 July 2020 | By Hannah Balfour (Drug Target Review)

The novel aryl hydrocarbon receptor (AHR) inhibiting drug slowed zika virus replication and prevented mouse foetuses malforming in infected mothers.

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Antibodies against viral disease: highlighting technologies behind COVID-19 antibody therapy

4 June 2020 | By Shalom Gurjar (OXGENE)

Amid the rush to develop an effective vaccine against COVID-19, antibody therapy has become a major strategy to ameliorate and treat cases of severe disease. Armed with the capacity to neutralise pathogens and orchestrate the immune system, promising antibody candidates for multiple viral indications, including HIV, continue to emerge. Technology…

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Significant breakthrough made in Zika virus vaccine development

16 December 2019 | By Rachael Harper (Drug Target Review)

Researchers have developed a novel T cell-based vaccine against the Zika virus that has proved effective in mouse models.

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Screening identifies gene which protects cells from Zika virus

26 July 2019 | By Victoria Rees (Drug Target Review)

Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.

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Biomarkers may predict Zika-related birth defects

5 November 2018 | By Drug Target Review

Researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus...

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Disrupting serotonin receptors to control spread of dengue and Zika

18 October 2018 | By Drug Target Review

Researchers are developing methos to decrease the body size and weight of mosquitoes in order to control the spread of dengue and Zika...

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Novel vaccine approach proves powerful against Zika virus

9 August 2018 | By Drug Target Review

VSV acted as a vehicle to deliver the genes of some proteins from the Zika virus into mouse models, leading to immunity build up in the mice...

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DNA-based Zika vaccine found effective at inducing immune response

5 October 2017 | By Dr Zara Kassam (Drug Target Review)

A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...

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PET imaging used to track Zika virus infection

20 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have used PET imaging to study brain inflammation following Zika virus infection in mice, allowing investigators to study the progression of the disease over time...

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Proteomics accurately detect exposure to Zika virus

22 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used proteomics to examine proteins and peptides in saliva to accurately detect exposure to Zika virus...

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Potential broad-spectrum antiviral discovery for herpes virus

16 August 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...

news

Scientists to test Zika virus on brain tumours

19 May 2017 | By Niamh Marriott (Drug Target Review)

The research, using tumour cells in the laboratory and in mice, will see if the Zika virus can destroy cancer cells.

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Researchers identify potential Zika Virus target

5 May 2017 | By Niamh Marriott (Drug Target Review)

New research provides insights into why infection with Zika virus after birth generally causes only mild symptoms, whereas devastating foetal malformations can develop when infection occurs during pregnancy.

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Abeome and CDC to collaborate on Zika antibody discovery

19 April 2017 | By Niamh Marriott (Drug Target Review)

The Zika virus, which is spread to people primarily through the bite of an infected Aedes species mosquito, is an impending threat to America’s borders, with over 5000 cases now reported in the continental US. Zika virus infection has been associated with Guillain-Barré Syndrome, and infection during pregnancy has been…

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BMBF funds Zika vaccine research group at LMU

8 February 2017 | By Niamh Marriott (Drug Target Review)

The research group will explore novel approaches to vaccine development, focusing on the Zika virus.

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Zika virus